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CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes.
Adler BA, Trinidad MI, Bellieny-Rabelo D, Zhang E, Karp HM, Skopintsev P, Thornton BW, Weissman RF, Yoon PH, Chen L, Hessler T, Eggers AR, Colognori D, Boger R, Doherty EE, Tsuchida CA, Tran RV, Hofman L, Shi H, Wasko KM, Zhou Z, Xia C, Al-Shimary MJ, Patel JR, Thomas VCJX, Pattali R, Kan MJ, Vardapetyan A, Yang A, Lahiri A, Maxwell MF, Murdock AG, Ramit GC, Henderson HR, Calvert RW, Bamert RS, Knott GJ, Lapinaite A, Pausch P, Cofsky JC, Sontheimer EJ, Wiedenheft B, Fineran PC, Brouns SJJ, Sashital DG, Thomas BC, Brown CT, Goltsman DSA, Barrangou R, Siksnys V, Banfield JF, Savage DF, Doudna JA. Adler BA, et al. Among authors: sashital dg. Nucleic Acids Res. 2024 Jan 5;52(D1):D590-D596. doi: 10.1093/nar/gkad890. Nucleic Acids Res. 2024. PMID: 37889041 Free PMC article.
Structural insights into RNA interference.
Sashital DG, Doudna JA. Sashital DG, et al. Curr Opin Struct Biol. 2010 Feb;20(1):90-7. doi: 10.1016/j.sbi.2009.12.001. Epub 2010 Jan 5. Curr Opin Struct Biol. 2010. PMID: 20053548 Free PMC article. Review.
CRISPR interference and priming varies with individual spacer sequences.
Xue C, Seetharam AS, Musharova O, Severinov K, Brouns SJ, Severin AJ, Sashital DG. Xue C, et al. Among authors: sashital dg. Nucleic Acids Res. 2015 Dec 15;43(22):10831-47. doi: 10.1093/nar/gkv1259. Epub 2015 Nov 19. Nucleic Acids Res. 2015. PMID: 26586800 Free PMC article.
CRISPR-Cas12a exhibits metal-dependent specificity switching.
Nguyen GT, Schelling MA, Raju A, Buscher KA, Sritharan A, Sashital DG. Nguyen GT, et al. Among authors: sashital dg. Nucleic Acids Res. 2024 Sep 9;52(16):9343-9359. doi: 10.1093/nar/gkae613. Nucleic Acids Res. 2024. PMID: 39019776 Free PMC article.
Pathogen detection in the CRISPR-Cas era.
Sashital DG. Sashital DG. Genome Med. 2018 Apr 24;10(1):32. doi: 10.1186/s13073-018-0543-4. Genome Med. 2018. PMID: 29690921 Free PMC article. Review.
40 results