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Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells.
Doshi MB, Lee N, Tseyang T, Ponomarova O, Goel HL, Spears M, Li R, Zhu LJ, Ashwood C, Simin K, Jang C, Mercurio AM, Walhout AJM, Spinelli JB, Kim D. Doshi MB, et al. Among authors: kim d. Nature. 2023 Nov;623(7987):625-632. doi: 10.1038/s41586-023-06676-3. Epub 2023 Oct 25. Nature. 2023. PMID: 37880368 Free PMC article.
Cancer Metabolism: Fueling More than Just Growth.
Lee N, Kim D. Lee N, et al. Among authors: kim d. Mol Cells. 2016 Dec;39(12):847-854. doi: 10.14348/molcells.2016.0310. Epub 2016 Dec 29. Mol Cells. 2016. PMID: 28030896 Free PMC article. Review.
Selenium detoxification is required for cancer-cell survival.
Carlisle AE, Lee N, Matthew-Onabanjo AN, Spears ME, Park SJ, Youkana D, Doshi MB, Peppers A, Li R, Joseph AB, Smith M, Simin K, Zhu LJ, Greer PL, Shaw LM, Kim D. Carlisle AE, et al. Among authors: kim d. Nat Metab. 2020 Jul;2(7):603-611. doi: 10.1038/s42255-020-0224-7. Epub 2020 Jul 6. Nat Metab. 2020. PMID: 32694795 Free PMC article.
De novo sphingolipid biosynthesis necessitates detoxification in cancer cells.
Spears ME, Lee N, Hwang S, Park SJ, Carlisle AE, Li R, Doshi MB, Armando AM, Gao J, Simin K, Zhu LJ, Greer PL, Quehenberger O, Torres EM, Kim D. Spears ME, et al. Among authors: kim d. Cell Rep. 2022 Sep 27;40(13):111415. doi: 10.1016/j.celrep.2022.111415. Cell Rep. 2022. PMID: 36170811 Free PMC article.
Selenium reduction of ubiquinone via SQOR suppresses ferroptosis.
Lee N, Park SJ, Lange M, Tseyang T, Doshi MB, Kim TY, Song Y, Kim DI, Greer PL, Olzmann JA, Spinelli JB, Kim D. Lee N, et al. Among authors: kim ty, kim di, kim d. Nat Metab. 2024 Feb;6(2):343-358. doi: 10.1038/s42255-024-00974-4. Epub 2024 Feb 13. Nat Metab. 2024. PMID: 38351124
55,137 results
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