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A novel ultrasensitive assay for plasma p-tau217: performance in individuals with subjective cognitive decline and early Alzheimer's disease.
Gonzalez-Ortiz F, Ferreira PCL, Gonzalez A, Montoliu-Gaya L, Ortiz-Romero P, Kac PR, Turton M, Kvartsberg H, Ashton NJ, Zetterberg H, Harrison P, Bellaver B, Povala G, Villemagne VL, Pascoal TA, Ganguli M, Cohen AD, Miguillon C, Contador J, Suarez-Calvet M, Karikari TK, Blennow K. Gonzalez-Ortiz F, et al. Among authors: cohen ad. medRxiv [Preprint]. 2023 Oct 5:2023.09.26.23296134. doi: 10.1101/2023.09.26.23296134. medRxiv. 2023. Update in: Alzheimers Dement. 2024 Feb;20(2):1239-1249. doi: 10.1002/alz.13525. PMID: 37873312 Free PMC article. Updated. Preprint.
Novel CYP1B1-RMDN2 Alzheimer's disease locus identified by genome-wide association analysis of cerebral tau deposition on PET.
Nho K, Risacher SL, Apostolova L, Bice PJ, Brosch J, Deardorff R, Faber K, Farlow MR, Foroud T, Gao S, Rosewood T, Kim JP, Nudelman K, Yu M, Aisen P, Sperling R, Hooli B, Shcherbinin S, Svaldi D, Jack CR, Jagust WJ, Landau S, Vasanthakumar A, Waring JF, Doré V, Laws SM, Masters CL, Porter T, Rowe CC, Villemagne VL, Dumitrescu L, Hohman TJ, Libby JB, Mormino E, Buckley RF, Johnson K, Yang HS, Petersen RC, Ramanan VK, Vemuri P, Cohen AD, Fan KH, Kamboh MI, Lopez OL, Bennett DA, Ali M, Benzinger T, Cruchaga C, Hobbs D, De Jager PL, Fujita M, Jadhav V, Lamb BT, Tsai AP, Castanho I, Mill J, Weiner MW; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer’s Disease Neuroimaging Initiative – Department of Defense; Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study); Australian Imaging, Biomarker & Lifestyle Study (AIBL); Saykin AJ. Nho K, et al. Among authors: cohen ad. medRxiv [Preprint]. 2023 Mar 22:2023.02.27.23286048. doi: 10.1101/2023.02.27.23286048. medRxiv. 2023. PMID: 36993271 Free PMC article. Preprint.
Rethinking the residual approach: Leveraging machine learning to operationalize cognitive resilience in Alzheimer's disease.
Birkenbihl C, Cuppels M, Boyle RT, Klinger HM, Langford O, Coughlan GT, Properzi MJ, Chhatwal J, Price JC, Schultz AP, Rentz DM, Amariglio RE, Johnson KA, Gottesman RF, Mukherjee S, Maruff P, Lim YY, Masters CL, Beiser A, Resnick SM, Hughes TM, Burnham S, Tunali I, Landau S, Cohen AD, Johnson SC, Betthauser TJ, Seshadri S, Lockhart SN, O'Bryant SE, Vemuri P, Sperling RA, Hohman TJ, Donohue MC, Buckley RF. Birkenbihl C, et al. Among authors: cohen ad. medRxiv [Preprint]. 2024 Sep 18:2024.08.19.24312256. doi: 10.1101/2024.08.19.24312256. medRxiv. 2024. PMID: 39228697 Free PMC article. Preprint.
Complex Regulation of Protocadherin Epigenetics on Aging-Related Brain Health.
Schmithorst V, Bais A, Badaly D, Williams K, Gabriel G, Ceschin R, Wallace J, Lee V, Lopez O, Cohen A, Martin LJ, Lo C, Panigrahy A. Schmithorst V, et al. medRxiv [Preprint]. 2024 Apr 22:2024.04.21.24306143. doi: 10.1101/2024.04.21.24306143. medRxiv. 2024. PMID: 38712165 Free PMC article. Preprint.
The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome.
Xicota L, Dang LT, Lee A, Krinsky-McHale S, Pang D, Melilli L, O'Bryant S, Henson RL, Laymon C, Lai F, Rosas HD, Ances B, Lott I, Hom C, Christian B, Hartley S, Zaman S, Head E, Mapstone M, Jin Z, Silverman W, Schupf N, Handen B, Lee JH; Alzheimer's Biomarker Consortium – Down Syndrome (ABC-DS). Xicota L, et al. EBioMedicine. 2024 Nov 4;110:105433. doi: 10.1016/j.ebiom.2024.105433. Online ahead of print. EBioMedicine. 2024. PMID: 39500037 Free article.
Cerebrovascular disease is associated with Alzheimer's plasma biomarker concentrations in adults with Down syndrome.
Edwards NC, Lao PJ, Alshikho MJ, Ericsson OM, Rizvi B, Petersen ME, O'Bryant S, Aguilar LF, Simoes S, Mapstone M, Tudorascu DL, Janelidze S, Hansson O, Handen BL, Christian BT, Lee JH, Lai F, Rosas HD, Zaman S, Lott IT, Yassa MA; Alzheimer’s Biomarkers Consortium–Down Syndrome (ABC-DS) Investigators; Gutierrez J, Wilcock DM, Head E, Brickman AM. Edwards NC, et al. Brain Commun. 2024 Sep 25;6(5):fcae331. doi: 10.1093/braincomms/fcae331. eCollection 2024. Brain Commun. 2024. PMID: 39403075 Free PMC article.
Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease.
Zeng X, Lafferty TK, Sehrawat A, Chen Y, Ferreira PCL, Bellaver B, Povala G, Kamboh MI, Klunk WE, Cohen AD, Lopez OL, Ikonomovic MD, Pascoal TA, Ganguli M, Villemagne VL, Snitz BE, Karikari TK. Zeng X, et al. Among authors: cohen ad. Mol Neurodegener. 2024 Oct 10;19(1):68. doi: 10.1186/s13024-024-00753-5. Mol Neurodegener. 2024. PMID: 39385222 Free PMC article.
Giant cell arteritis (GCA) as a risk factor for seizures: a cohort study.
David P, Houri Levi E, Feifel A, Patt YS, Watad A, Gendelman O, Cohen AD, Amital H, Tsur AM. David P, et al. Among authors: cohen ad. Postgrad Med. 2024 Oct 7:1-8. doi: 10.1080/00325481.2024.2413355. Online ahead of print. Postgrad Med. 2024. PMID: 39365665
678 results