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Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation.
Jing Y, Jiang X, Ji Q, Wu Z, Wang W, Liu Z, Guillen-Garcia P, Esteban CR, Reddy P, Horvath S, Li J, Geng L, Hu Q, Wang S, Belmonte JCI, Ren J, Zhang W, Qu J, Liu GH. Jing Y, et al. Among authors: liu z, liu gh. Cell Stem Cell. 2023 Nov 2;30(11):1452-1471.e10. doi: 10.1016/j.stem.2023.09.007. Epub 2023 Oct 12. Cell Stem Cell. 2023. PMID: 37832549 Free article.
Vitamin C alleviates aging defects in a stem cell model for Werner syndrome.
Li Y, Zhang W, Chang L, Han Y, Sun L, Gong X, Tang H, Liu Z, Deng H, Ye Y, Wang Y, Li J, Qiao J, Qu J, Zhang W, Liu GH. Li Y, et al. Among authors: liu z, liu gh. Protein Cell. 2016 Jul;7(7):478-88. doi: 10.1007/s13238-016-0278-1. Epub 2016 Jun 6. Protein Cell. 2016. PMID: 27271327 Free PMC article.
Chemical screen identifies a geroprotective role of quercetin in premature aging.
Geng L, Liu Z, Zhang W, Li W, Wu Z, Wang W, Ren R, Su Y, Wang P, Sun L, Ju Z, Chan P, Song M, Qu J, Liu GH. Geng L, et al. Among authors: liu z, liu gh. Protein Cell. 2019 Jun;10(6):417-435. doi: 10.1007/s13238-018-0567-y. Epub 2018 Aug 1. Protein Cell. 2019. PMID: 30069858 Free PMC article.
SIRT6 deficiency results in developmental retardation in cynomolgus monkeys.
Zhang W, Wan H, Feng G, Qu J, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang Z, Yuan Y, Zhou Q, Li W, Liu GH, Hu B. Zhang W, et al. Among authors: liu z, liu gh. Nature. 2018 Aug;560(7720):661-665. doi: 10.1038/s41586-018-0437-z. Epub 2018 Aug 22. Nature. 2018. PMID: 30135584
Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis.
Fu L, Hu Y, Song M, Liu Z, Zhang W, Yu FX, Wu J, Wang S, Izpisua Belmonte JC, Chan P, Qu J, Tang F, Liu GH. Fu L, et al. Among authors: liu z, liu gh. PLoS Biol. 2019 Apr 1;17(4):e3000201. doi: 10.1371/journal.pbio.3000201. eCollection 2019 Apr. PLoS Biol. 2019. PMID: 30933975 Free PMC article.
89,167 results
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