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Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation.
Jing Y, Jiang X, Ji Q, Wu Z, Wang W, Liu Z, Guillen-Garcia P, Esteban CR, Reddy P, Horvath S, Li J, Geng L, Hu Q, Wang S, Belmonte JCI, Ren J, Zhang W, Qu J, Liu GH. Jing Y, et al. Among authors: esteban cr. Cell Stem Cell. 2023 Nov 2;30(11):1452-1471.e10. doi: 10.1016/j.stem.2023.09.007. Epub 2023 Oct 12. Cell Stem Cell. 2023. PMID: 37832549 Free article.
A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence.
Wang W, Zheng Y, Sun S, Li W, Song M, Ji Q, Wu Z, Liu Z, Fan Y, Liu F, Li J, Esteban CR, Wang S, Zhou Q, Belmonte JCI, Zhang W, Qu J, Tang F, Liu GH. Wang W, et al. Among authors: esteban cr. Sci Transl Med. 2021 Jan 6;13(575):eabd2655. doi: 10.1126/scitranslmed.abd2655. Sci Transl Med. 2021. PMID: 33408182
Single-Cell Transcriptomic Atlas of Primate Ovarian Aging.
Wang S, Zheng Y, Li J, Yu Y, Zhang W, Song M, Liu Z, Min Z, Hu H, Jing Y, He X, Sun L, Ma L, Esteban CR, Chan P, Qiao J, Zhou Q, Izpisua Belmonte JC, Qu J, Tang F, Liu GH. Wang S, et al. Among authors: esteban cr. Cell. 2020 Feb 6;180(3):585-600.e19. doi: 10.1016/j.cell.2020.01.009. Epub 2020 Jan 30. Cell. 2020. PMID: 32004457 Free article.
Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming.
Yan P, Liu Z, Song M, Wu Z, Xu W, Li K, Ji Q, Wang S, Liu X, Yan K, Esteban CR, Ci W, Belmonte JCI, Xie W, Ren J, Zhang W, Sun Q, Qu J, Liu GH. Yan P, et al. Among authors: esteban cr. Cell Rep. 2020 Jul 7;32(1):107870. doi: 10.1016/j.celrep.2020.107870. Cell Rep. 2020. PMID: 32640235 Free article.
A Single-Cell Transcriptomic Atlas of Human Skin Aging.
Zou Z, Long X, Zhao Q, Zheng Y, Song M, Ma S, Jing Y, Wang S, He Y, Esteban CR, Yu N, Huang J, Chan P, Chen T, Izpisua Belmonte JC, Zhang W, Qu J, Liu GH. Zou Z, et al. Among authors: esteban cr. Dev Cell. 2021 Feb 8;56(3):383-397.e8. doi: 10.1016/j.devcel.2020.11.002. Epub 2020 Nov 24. Dev Cell. 2021. PMID: 33238152 Free article.
Resurrection of endogenous retroviruses during aging reinforces senescence.
Liu X, Liu Z, Wu Z, Ren J, Fan Y, Sun L, Cao G, Niu Y, Zhang B, Ji Q, Jiang X, Wang C, Wang Q, Ji Z, Li L, Esteban CR, Yan K, Li W, Cai Y, Wang S, Zheng A, Zhang YE, Tan S, Cai Y, Song M, Lu F, Tang F, Ji W, Zhou Q, Belmonte JCI, Zhang W, Qu J, Liu GH. Liu X, et al. Among authors: esteban cr. Cell. 2023 Jan 19;186(2):287-304.e26. doi: 10.1016/j.cell.2022.12.017. Epub 2023 Jan 6. Cell. 2023. PMID: 36610399 Free article.
Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones.
Suzuki K, Yu C, Qu J, Li M, Yao X, Yuan T, Goebl A, Tang S, Ren R, Aizawa E, Zhang F, Xu X, Soligalla RD, Chen F, Kim J, Kim NY, Liao HK, Benner C, Esteban CR, Jin Y, Liu GH, Li Y, Izpisua Belmonte JC. Suzuki K, et al. Among authors: esteban cr. Cell Stem Cell. 2014 Jul 3;15(1):31-6. doi: 10.1016/j.stem.2014.06.016. Cell Stem Cell. 2014. PMID: 24996168 Free PMC article.
45 results