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Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Cell. 2023 Oct 26;186(22):4898-4919.e25. doi: 10.1016/j.cell.2023.09.008. Epub 2023 Oct 11.
Cell. 2023.
PMID: 37827155
A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo.
Nakamori M, Panigrahi GB, Lanni S, Gall-Duncan T, Hayakawa H, Tanaka H, Luo J, Otabe T, Li J, Sakata A, Caron MC, Joshi N, Prasolava T, Chiang K, Masson JY, Wold MS, Wang X, Lee MYWT, Huddleston J, Munson KM, Davidson S, Layeghifard M, Edward LM, Gallon R, Santibanez-Koref M, Murata A, Takahashi MP, Eichler EE, Shlien A, Nakatani K, Mochizuki H, Pearson CE.
Nakamori M, et al. Among authors: gall duncan t.
Nat Genet. 2020 Feb;52(2):146-159. doi: 10.1038/s41588-019-0575-8. Epub 2020 Feb 14.
Nat Genet. 2020.
PMID: 32060489
Free PMC article.
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Advancing genomic technologies and clinical awareness accelerates discovery of disease-associated tandem repeat sequences.
Gall-Duncan T, Sato N, Yuen RKC, Pearson CE.
Gall-Duncan T, et al.
Genome Res. 2022 Jan;32(1):1-27. doi: 10.1101/gr.269530.120. Epub 2021 Dec 29.
Genome Res. 2022.
PMID: 34965938
Free PMC article.
Review.
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CAG repeat-binding small molecule improves motor coordination impairment in a mouse model of Dentatorubral-pallidoluysian atrophy.
Hasuike Y, Tanaka H, Gall-Duncan T, Mehkary M, Nakatani K, Pearson CE, Tsuji S, Mochizuki H, Nakamori M.
Hasuike Y, et al. Among authors: gall duncan t.
Neurobiol Dis. 2022 Feb;163:105604. doi: 10.1016/j.nbd.2021.105604. Epub 2021 Dec 28.
Neurobiol Dis. 2022.
PMID: 34968706
Free article.
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Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies.
Wright GEB, Black HF, Collins JA, Gall-Duncan T, Caron NS, Pearson CE, Hayden MR.
Wright GEB, et al. Among authors: gall duncan t.
Lancet Neurol. 2020 Nov;19(11):930-939. doi: 10.1016/S1474-4422(20)30343-4.
Lancet Neurol. 2020.
PMID: 33098802
Review.
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Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31.
Ishiguro T, Sato N, Ueyama M, Fujikake N, Sellier C, Kanegami A, Tokuda E, Zamiri B, Gall-Duncan T, Mirceta M, Furukawa Y, Yokota T, Wada K, Taylor JP, Pearson CE, Charlet-Berguerand N, Mizusawa H, Nagai Y, Ishikawa K.
Ishiguro T, et al. Among authors: gall duncan t.
Neuron. 2017 Apr 5;94(1):108-124.e7. doi: 10.1016/j.neuron.2017.02.046. Epub 2017 Mar 23.
Neuron. 2017.
PMID: 28343865
Free PMC article.
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Huntingtin is an RNA binding protein and participates in NEAT1-mediated paraspeckles.
Yadav M, Harding RJ, Li T, Xu X, Gall-Duncan T, Khan M, Bardile CF, Sequiera GL, Duan S, Chandrasekaran R, Pan A, Bu J, Yamazaki T, Hirose T, Prinos P, Tippett L, Turner C, Curtis MA, Faull RLM, Pouladi MA, Pearson CE, He HH, Arrowsmith CH.
Yadav M, et al. Among authors: gall duncan t.
Sci Adv. 2024 Jul 19;10(29):eado5264. doi: 10.1126/sciadv.ado5264. Epub 2024 Jul 19.
Sci Adv. 2024.
PMID: 39028820
Free PMC article.
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