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Characterization of the antispike IgG immune response to COVID-19 vaccines in people with a wide variety of immunodeficiencies.
Zendt M, Bustos Carrillo FA, Kelly S, Saturday T, DeGrange M, Ginigeme A, Wu L, Callier V, Ortega-Villa A, Faust M, Chang-Rabley E, Bugal K, Kenney H, Khil P, Youn JH, Osei G, Regmi P, Anderson V, Bosticardo M, Daub J, DiMaggio T, Kreuzburg S, Pala F, Pfister J, Treat J, Ulrick J, Karkanitsa M, Kalish H, Kuhns DB, Priel DL, Fink DL, Tsang JS, Sparks R, Uzel G, Waldman MA, Zerbe CS, Delmonte OM, Bergerson JRE, Das S, Freeman AF, Lionakis MS, Sadtler K, van Doremalen N, Munster V, Notarangelo LD, Holland SM, Ricotta EE. Zendt M, et al. Among authors: sparks r. Sci Adv. 2023 Oct 13;9(41):eadh3150. doi: 10.1126/sciadv.adh3150. Epub 2023 Oct 12. Sci Adv. 2023. PMID: 37824621 Free PMC article.
Multiomics integration of 22 immune-mediated monogenic diseases reveals an emergent axis of human immune health.
Sparks R, Rachmaninoff N, Hirsch DC, Bansal N, Lau WW, Martins AJ, Chen J, Liu CC, Cheung F, Failla LE, Biancotto A, Fantoni G, Sellers BA, Chawla DG, Howe KN, Mostaghimi D, Farmer R, Kotliarov Y, Calvo KR, Palmer C, Daub J, Foruraghi L, Kreuzburg S, Treat J, Urban AK, Jones A, Romeo T, Deuitch NT, Moura NS, Weinstein B, Moir S, Ferrucci L, Barron KS, Aksentijevich I, Kleinstein SH, Townsley DM, Young NS, Frischmeyer-Guerrerio PA, Uzel G, Pinto-Patarroyo GP, Cudrici CD, Hoffmann P, Stone DL, Ombrello AK, Freeman AF, Zerbe CS, Kastner DL, Holland SM, Tsang JS. Sparks R, et al. Res Sq [Preprint]. 2023 Mar 20:rs.3.rs-2070975. doi: 10.21203/rs.3.rs-2070975/v1. Res Sq. 2023. Update in: Nat Med. 2024 Jul 3. doi: 10.1038/s41591-024-03092-6. PMID: 36993430 Free PMC article. Updated. Preprint.
A unified metric of human immune health.
Sparks R, Rachmaninoff N, Lau WW, Hirsch DC, Bansal N, Martins AJ, Chen J, Liu CC, Cheung F, Failla LE, Biancotto A, Fantoni G, Sellers BA, Chawla DG, Howe KN, Mostaghimi D, Farmer R, Kotliarov Y, Calvo KR, Palmer C, Daub J, Foruraghi L, Kreuzburg S, Treat JD, Urban AK, Jones A, Romeo T, Deuitch NT, Moura NS, Weinstein B, Moir S, Ferrucci L, Barron KS, Aksentijevich I, Kleinstein SH, Townsley DM, Young NS, Frischmeyer-Guerrerio PA, Uzel G, Pinto-Patarroyo GP, Cudrici CD, Hoffmann P, Stone DL, Ombrello AK, Freeman AF, Zerbe CS, Kastner DL, Holland SM, Tsang JS. Sparks R, et al. Nat Med. 2024 Sep;30(9):2461-2472. doi: 10.1038/s41591-024-03092-6. Epub 2024 Jul 3. Nat Med. 2024. PMID: 38961223
Influenza vaccination reveals sex dimorphic imprints of prior mild COVID-19.
Sparks R, Lau WW, Liu C, Han KL, Vrindten KL, Sun G, Cox M, Andrews SF, Bansal N, Failla LE, Manischewitz J, Grubbs G, King LR, Koroleva G, Leimenstoll S, Snow L; OP11 Clinical Staff; Chen J, Tang J, Mukherjee A, Sellers BA, Apps R, McDermott AB, Martins AJ, Bloch EM, Golding H, Khurana S, Tsang JS. Sparks R, et al. Nature. 2023 Feb;614(7949):752-761. doi: 10.1038/s41586-022-05670-5. Epub 2023 Jan 4. Nature. 2023. PMID: 36599369 Free PMC article.
Expert judgement reveals current and emerging UK climate-mortality burden.
Mitchell D, Lo YTE, Ball E, Godwin JL, Andrews O, Barciela R, Ford LB, Di Napoli C, Ebi KL, Fučkar NS, Gasparrini A, Golding B, Gregson CL, Griffith GJ, Khalid S, Robinson C, Schmidt DN, Simpson CH, Sparks RSJ, Walker JG. Mitchell D, et al. Among authors: sparks rsj. Lancet Planet Health. 2024 Sep;8(9):e684-e694. doi: 10.1016/S2542-5196(24)00175-X. Lancet Planet Health. 2024. PMID: 39243784 Free article. Review.
Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs.
Sun C, Zhou C, Daneshvar K, Ben Saad A, Kratkiewicz AJ, Toles BJ, Arghiani N, Hess A, Chen JY, Pondick JV, York SR, Li W, Moran SP, Gentile SD, Rahman RU, Li Z, Zhou P, Sparks RP, Habboub T, Kim BM, Choi MY, Affo S, Schwabe RF, Popov YV, Mullen AC. Sun C, et al. Among authors: sparks rp. Hepatology. 2024 Apr 2. doi: 10.1097/HEP.0000000000000822. Online ahead of print. Hepatology. 2024. PMID: 38563629
First-in-Human Safety, Imaging, and Dosimetry of a Carbonic Anhydrase IX-Targeting Peptide, [68Ga]Ga-DPI-4452, in Patients with Clear Cell Renal Cell Carcinoma.
Hofman MS, Tran B, Feldman DR, Pokorska-Bocci A, Pichereau S, Wessen J, Haskali MB, Sparks RB, Vlasyuk O, Galetic I. Hofman MS, et al. Among authors: sparks rb. J Nucl Med. 2024 Feb 22;65(5):740-3. doi: 10.2967/jnumed.123.267175. Online ahead of print. J Nucl Med. 2024. PMID: 38388517 Free PMC article.
439 results