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Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Victorelli S, et al. Among authors: gavathiotis e. Nature. 2023 Oct;622(7983):627-636. doi: 10.1038/s41586-023-06621-4. Epub 2023 Oct 11. Nature. 2023. PMID: 37821702 Free PMC article.
Tracking BAX once its trigger is pulled.
Gavathiotis E, Walensky LD. Gavathiotis E, et al. Cell Cycle. 2011 Mar 15;10(6):868-70. doi: 10.4161/cc.10.6.15034. Epub 2011 Mar 15. Cell Cycle. 2011. PMID: 21325897 Free PMC article. No abstract available.
A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.
LaBelle JL, Katz SG, Bird GH, Gavathiotis E, Stewart ML, Lawrence C, Fisher JK, Godes M, Pitter K, Kung AL, Walensky LD. LaBelle JL, et al. Among authors: gavathiotis e. J Clin Invest. 2012 Jun;122(6):2018-31. doi: 10.1172/JCI46231. Epub 2012 May 24. J Clin Invest. 2012. PMID: 22622039 Free PMC article.
Editorial overview: Chemical genetics and epigenetics.
Gavathiotis E, Zhou MM. Gavathiotis E, et al. Curr Opin Chem Biol. 2017 Aug;39:vi-vii. doi: 10.1016/j.cbpa.2017.07.004. Epub 2017 Aug 8. Curr Opin Chem Biol. 2017. PMID: 28801102 No abstract available.
91 results