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DNA-encoded library-enabled discovery of proximity-inducing small molecules.
Mason JW, Chow YT, Hudson L, Tutter A, Michaud G, Westphal MV, Shu W, Ma X, Tan ZY, Coley CW, Clemons PA, Bonazzi S, Berst F, Briner K, Liu S, Zécri FJ, Schreiber SL. Mason JW, et al. Among authors: tutter a. Nat Chem Biol. 2024 Feb;20(2):170-179. doi: 10.1038/s41589-023-01458-4. Epub 2023 Nov 2. Nat Chem Biol. 2024. PMID: 37919549
Activation of human STING by a molecular glue-like compound.
Li J, Canham SM, Wu H, Henault M, Chen L, Liu G, Chen Y, Yu G, Miller HR, Hornak V, Brittain SM, Michaud GA, Tutter A, Broom W, Digan ME, McWhirter SM, Sivick KE, Pham HT, Chen CH, Tria GS, McKenna JM, Schirle M, Mao X, Nicholson TB, Wang Y, Jenkins JL, Jain RK, Tallarico JA, Patel SJ, Zheng L, Ross NT, Cho CY, Zhang X, Bai XC, Feng Y. Li J, et al. Among authors: tutter a. Nat Chem Biol. 2024 Mar;20(3):365-372. doi: 10.1038/s41589-023-01434-y. Epub 2023 Oct 12. Nat Chem Biol. 2024. PMID: 37828400 Free PMC article.
SEC-TID: A Label-Free Method for Small-Molecule Target Identification.
Salcius M, Bauer AJ, Hao Q, Li S, Tutter A, Raphael J, Jahnke W, Rondeau JM, Bourgier E, Tallarico J, Michaud GA. Salcius M, et al. Among authors: tutter a. J Biomol Screen. 2014 Jul;19(6):917-27. doi: 10.1177/1087057114522691. Epub 2014 Feb 19. J Biomol Screen. 2014. PMID: 24554445
Metabolic Enzyme Sulfotransferase 1A1 Is the Trigger for N-Benzyl Indole Carbinol Tumor Growth Suppression.
Rothman DM, Gao X, George E, Rasmusson T, Bhatia D, Alimov I, Wang L, Kamel A, Hatsis P, Feng Y, Tutter A, Michaud G, McDonald E 3rd, Venkatesan K, Farley D, Digan ME, Ni Y, Harbinski F, Gunduz M, Wilson CJ, Buckler A, Labow M, Tallarico J, Myer VE, Porter JA, Wang S. Rothman DM, et al. Among authors: tutter a. Chem Biol. 2015 Sep 17;22(9):1228-37. doi: 10.1016/j.chembiol.2015.06.025. Epub 2015 Sep 10. Chem Biol. 2015. PMID: 26364931
Role for Med12 in regulation of Nanog and Nanog target genes.
Tutter AV, Kowalski MP, Baltus GA, Iourgenko V, Labow M, Li E, Kadam S. Tutter AV, et al. J Biol Chem. 2009 Feb 6;284(6):3709-18. doi: 10.1074/jbc.M805677200. Epub 2008 Nov 26. J Biol Chem. 2009. PMID: 19036726 Free article.
39 results