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Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease.
Hung AM, Assimon VA, Chen HC, Yu Z, Vlasschaert C, Triozzi JL, Chan H, Wheless L, Wilson O, Shah SC, Mack T, Thompson T, Matheny ME, Chandrasekar S, Mozaffari SV, Chung CP, Tsao P, Susztak K, Siew ED, Estrada K, Gaziano JM, Graham RR, Tao R, Hoek M, Robinson-Cohen C, Green EM, Bick AG; Million Veteran Program. Hung AM, et al. Among authors: chen hc. J Am Soc Nephrol. 2023 Nov 1;34(11):1889-1899. doi: 10.1681/ASN.0000000000000219. Epub 2023 Oct 6. J Am Soc Nephrol. 2023. PMID: 37798822 Free PMC article.
APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis.
Wu J, Ma Z, Raman A, Beckerman P, Dhillon P, Mukhi D, Palmer M, Chen HC, Cohen CR, Dunn T, Reilly J, Meyer N, Shashaty M, Arany Z, Haskó G, Laudanski K, Hung A, Susztak K. Wu J, et al. Among authors: chen hc. Immunity. 2021 Nov 9;54(11):2632-2649.e6. doi: 10.1016/j.immuni.2021.10.004. Epub 2021 Oct 12. Immunity. 2021. PMID: 34715018 Free PMC article.
APOL1 Risk Variants, Acute Kidney Injury, and Death in Participants With African Ancestry Hospitalized With COVID-19 From the Million Veteran Program.
Hung AM, Shah SC, Bick AG, Yu Z, Chen HC, Hunt CM, Wendt F, Wilson O, Greevy RA, Chung CP, Suzuki A, Ho YL, Akwo E, Polimanti R, Zhou J, Reaven P, Tsao PS, Gaziano JM, Huffman JE, Joseph J, Luoh SW, Iyengar S, Chang KM, Casas JP, Matheny ME, O'Donnell CJ, Cho K, Tao R, Susztak K, Robinson-Cohen C, Tuteja S, Siew ED; VA Million Veteran Program COVID-19 Science Initiative. Hung AM, et al. Among authors: chen hc. JAMA Intern Med. 2022 Apr 1;182(4):386-395. doi: 10.1001/jamainternmed.2021.8538. JAMA Intern Med. 2022. PMID: 35089317 Free PMC article.
Genetic Variants Associated With Mineral Metabolism Traits in Chronic Kidney Disease.
Laster ML, Rowan B, Chen HC, Schwantes-An TH, Sheng X, Friedman PA, Ikizler TA, Sinshiemer JS, Ix JH, Susztak K, de Boer IH, Kestenbaum B, Hung A, Moe SM, Perwad F, Robinson-Cohen C. Laster ML, et al. Among authors: chen hc. J Clin Endocrinol Metab. 2022 Aug 18;107(9):e3866-e3876. doi: 10.1210/clinem/dgac318. J Clin Endocrinol Metab. 2022. PMID: 35587600 Free PMC article.
Pharmacogenetic variants and risk of remdesivir-associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID-19.
Tuteja S, Yu Z, Wilson O, Chen HC, Wendt F, Chung CP, Shah SC, Hunt CM, Suzuki A, Chanfreau C, Gorman BR, Joseph J, Luoh SW, Napolioni V, Robinson-Cohen C, Tao R, Zhou J, Chang KM, Hung AM; VA Million Veteran Program COVID-19 Science Initiative. Tuteja S, et al. Among authors: chen hc. Clin Transl Sci. 2022 Aug;15(8):1880-1886. doi: 10.1111/cts.13313. Epub 2022 Jun 9. Clin Transl Sci. 2022. PMID: 35684976 Free PMC article.
Phenome-Wide Association Study of UMOD Gene Variants and Differential Associations With Clinical Outcomes Across Populations in the Million Veteran Program a Multiethnic Biobank.
Akwo EA, Chen HC, Liu G, Triozzi JL, Tao R, Yu Z, Chung CP, Giri A, Ikizler TA, Stein CM, Siew ED, Feng Q, Robinson-Cohen C, Hung AM; VA Million Veteran Program. Akwo EA, et al. Among authors: chen hc. Kidney Int Rep. 2022 May 18;7(8):1802-1818. doi: 10.1016/j.ekir.2022.05.011. eCollection 2022 Aug. Kidney Int Rep. 2022. PMID: 35967117 Free PMC article.
Genetic Determinants of IL-6 Levels and Risk of ESKD.
Wheless L, Pike MM, Chen HC, Yu Z, Tao R, Bick A, Chung CP, Robinson-Cohen C, Hung A. Wheless L, et al. Among authors: chen hc. Kidney360. 2023 Feb 1;4(2):241-244. doi: 10.34067/KID.0003332022. Epub 2022 Dec 14. Kidney360. 2023. PMID: 36821615 Free PMC article.
GLP1R Gene Expression and Kidney Disease Progression.
Triozzi JL, Yu Z, Giri A, Chen HC, Wilson OD, Ferolito B, Ikizler TA, Akwo EA, Robinson-Cohen C, Gaziano JM, Cho K, Phillips LS, Tao R, Pereira AC, Hung AM; VA Million Veteran Program. Triozzi JL, et al. Among authors: chen hc. JAMA Netw Open. 2024 Oct 1;7(10):e2440286. doi: 10.1001/jamanetworkopen.2024.40286. JAMA Netw Open. 2024. PMID: 39453656 Free article.
4,141 results