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Page 1
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo.
Giannakopoulou E, Lehander M, Virding Culleton S, Yang W, Li Y, Karpanen T, Yoshizato T, Rustad EH, Nielsen MM, Bollineni RC, Tran TT, Delic-Sarac M, Gjerdingen TJ, Douvlataniotis K, Laos M, Ali M, Hillen A, Mazzi S, Chin DWL, Mehta A, Holm JS, Bentzen AK, Bill M, Griffioen M, Gedde-Dahl T, Lehmann S, Jacobsen SEW, Woll PS, Olweus J. Giannakopoulou E, et al. Among authors: olweus j. Nat Cancer. 2023 Oct;4(10):1474-1490. doi: 10.1038/s43018-023-00642-8. Epub 2023 Oct 2. Nat Cancer. 2023. PMID: 37783807 Free PMC article.
T-cell receptor gene therapy--ready to go viral?
Karpanen T, Olweus J. Karpanen T, et al. Among authors: olweus j. Mol Oncol. 2015 Dec;9(10):2019-42. doi: 10.1016/j.molonc.2015.10.006. Epub 2015 Oct 20. Mol Oncol. 2015. PMID: 26548533 Free PMC article. Review.
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.
Ali M, Giannakopoulou E, Li Y, Lehander M, Virding Culleton S, Yang W, Knetter C, Odabasi MC, Bollineni RC, Yang X, Foldvari Z, Böschen ML, Taraldsrud E, Strønen E, Toebes M, Hillen A, Mazzi S, de Ru AH, Janssen GMC, Kolstad A, Tjønnfjord GE, Lie BA, Griffioen M, Lehmann S, Osnes LT, Buechner J, Garcia KC, Schumacher TN, van Veelen PA, Leisegang M, Jacobsen SEW, Woll P, Olweus J. Ali M, et al. Among authors: olweus j. Nat Biotechnol. 2022 Apr;40(4):488-498. doi: 10.1038/s41587-021-01089-x. Epub 2021 Dec 6. Nat Biotechnol. 2022. PMID: 34873326 Free PMC article.
Chasing neoantigens; invite naïve T cells to the party.
Bollineni RC, Tran TT, Lund-Johansen F, Olweus J. Bollineni RC, et al. Among authors: olweus j. Curr Opin Immunol. 2022 Apr;75:102172. doi: 10.1016/j.coi.2022.102172. Epub 2022 Mar 10. Curr Opin Immunol. 2022. PMID: 35279483 Review.
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants.
Meyer S, Blaas I, Bollineni RC, Delic-Sarac M, Tran TT, Knetter C, Dai KZ, Madssen TS, Vaage JT, Gustavsen A, Yang W, Nissen-Meyer LSH, Douvlataniotis K, Laos M, Nielsen MM, Thiede B, Søraas A, Lund-Johansen F, Rustad EH, Olweus J. Meyer S, et al. Among authors: olweus j. Cell Rep. 2023 Jan 31;42(1):111995. doi: 10.1016/j.celrep.2023.111995. Epub 2023 Jan 9. Cell Rep. 2023. PMID: 36656713 Free PMC article.
Induction of neoantigen-reactive T cells from healthy donors.
Ali M, Foldvari Z, Giannakopoulou E, Böschen ML, Strønen E, Yang W, Toebes M, Schubert B, Kohlbacher O, Schumacher TN, Olweus J. Ali M, et al. Among authors: olweus j. Nat Protoc. 2019 Jun;14(6):1926-1943. doi: 10.1038/s41596-019-0170-6. Epub 2019 May 17. Nat Protoc. 2019. PMID: 31101906
A systematic safety pipeline for selection of T-cell receptors to enter clinical use.
Foldvari Z, Knetter C, Yang W, Gjerdingen TJ, Bollineni RC, Tran TT, Lund-Johansen F, Kolstad A, Drousch K, Klopfleisch R, Leisegang M, Olweus J. Foldvari Z, et al. Among authors: olweus j. NPJ Vaccines. 2023 Aug 22;8(1):126. doi: 10.1038/s41541-023-00713-y. NPJ Vaccines. 2023. PMID: 37607971 Free PMC article.
Anti-tumour immunity induces aberrant peptide presentation in melanoma.
Bartok O, Pataskar A, Nagel R, Laos M, Goldfarb E, Hayoun D, Levy R, Körner PR, Kreuger IZM, Champagne J, Zaal EA, Bleijerveld OB, Huang X, Kenski J, Wargo J, Brandis A, Levin Y, Mizrahi O, Alon M, Lebon S, Yang W, Nielsen MM, Stern-Ginossar N, Altelaar M, Berkers CR, Geiger T, Peeper DS, Olweus J, Samuels Y, Agami R. Bartok O, et al. Among authors: olweus j. Nature. 2021 Feb;590(7845):332-337. doi: 10.1038/s41586-020-03054-1. Epub 2020 Dec 16. Nature. 2021. PMID: 33328638
Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.
Pataskar A, Champagne J, Nagel R, Kenski J, Laos M, Michaux J, Pak HS, Bleijerveld OB, Mordente K, Navarro JM, Blommaert N, Nielsen MM, Lovecchio D, Stone E, Georgiou G, de Gooijer MC, van Tellingen O, Altelaar M, Joosten RP, Perrakis A, Olweus J, Bassani-Sternberg M, Peeper DS, Agami R. Pataskar A, et al. Among authors: olweus j. Nature. 2022 Mar;603(7902):721-727. doi: 10.1038/s41586-022-04499-2. Epub 2022 Mar 9. Nature. 2022. PMID: 35264796 Free PMC article.
65 results