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Genome-wide association study of antisocial personality disorder diagnostic criteria provides evidence for shared risk factors across disorders.
Li W, Zhou H, Thygesen JH, Heydtmann M, Smith I, Degenhardt F, Nöthen M, Morgan MY, Kranzler HR, Gelernter J, Bass N, McQuillin A. Li W, et al. Among authors: zhou h. Psychiatr Genet. 2023 Dec 1;33(6):233-242. doi: 10.1097/YPG.0000000000000352. Epub 2023 Sep 19. Psychiatr Genet. 2023. PMID: 37756443 Free PMC article.
Genome-Wide Investigation of Maximum Habitual Alcohol Intake in US Veterans in Relation to Alcohol Consumption Traits and Alcohol Use Disorder.
Deak JD, Levey DF, Wendt FR, Zhou H, Galimberti M, Kranzler HR, Gaziano JM, Stein MB, Polimanti R, Gelernter J; Million Veteran Program. Deak JD, et al. Among authors: zhou h. JAMA Netw Open. 2022 Oct 3;5(10):e2238880. doi: 10.1001/jamanetworkopen.2022.38880. JAMA Netw Open. 2022. PMID: 36301540 Free PMC article.
Multi-ancestry study of the genetics of problematic alcohol use in >1 million individuals.
Zhou H, Kember RL, Deak JD, Xu H, Toikumo S, Yuan K, Lind PA, Farajzadeh L, Wang L, Hatoum AS, Johnson J, Lee H, Mallard TT, Xu J, Johnston KJA, Johnson EC, Galimberti M, Dao C, Levey DF, Overstreet C, Byrne EM, Gillespie NA, Gordon S, Hickie IB, Whitfield JB, Xu K, Zhao H, Huckins LM, Davis LK, Sanchez-Roige S, Madden PAF, Heath AC, Medland SE, Martin NG, Ge T, Smoller JW, Hougaard DM, Børglum AD, Demontis D, Krystal JH, Gaziano JM, Edenberg HJ, Agrawal A; Million Veteran Program; Justice AC, Stein MB, Kranzler HR, Gelernter J. Zhou H, et al. medRxiv [Preprint]. 2023 Jan 30:2023.01.24.23284960. doi: 10.1101/2023.01.24.23284960. medRxiv. 2023. Update in: Nat Med. 2023 Dec;29(12):3184-3192. doi: 10.1038/s41591-023-02653-5 PMID: 36747741 Free PMC article. Updated. Preprint.
The genetic architecture of pain intensity in a sample of 598,339 U.S. veterans.
Toikumo S, Vickers-Smith R, Jinwala Z, Xu H, Saini D, Hartwell E, Venegas MP, Sullivan KA, Xu K, Jacobson DA, Gelernter J, Rentsch CT; Million Veteran Program; Stahl E, Cheatle M, Zhou H, Waxman SG, Justice AC, Kember RL, Kranzler HR. Toikumo S, et al. Among authors: zhou h. medRxiv [Preprint]. 2023 Mar 13:2023.03.09.23286958. doi: 10.1101/2023.03.09.23286958. medRxiv. 2023. PMID: 36993749 Free PMC article. Preprint.
Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.
Toikumo S, Jennings MV, Pham BK, Lee H, Mallard TT, Bianchi SB, Meredith JJ, Vilar-Ribó L, Xu H, Hatoum AS, Johnson EC, Pazdernik V, Jinwala Z, Pakala SR, Leger BS, Niarchou M, Ehinmowo M; Penn Medicine BioBank, Million Veteran Program, PsycheMERGE Substance Use Disorder Workgroup; Jenkins GD, Batzler A, Pendegraft R, Palmer AA, Zhou H, Biernacka JM, Coombes BJ, Gelernter J, Xu K, Hancock DB, Cox NJ, Smoller JW, Davis LK, Justice AC, Kranzler HR, Kember RL, Sanchez-Roige S. Toikumo S, et al. Among authors: zhou h. medRxiv [Preprint]. 2023 Sep 18:2023.03.27.23287713. doi: 10.1101/2023.03.27.23287713. medRxiv. 2023. Update in: Nat Hum Behav. 2024 Jun;8(6):1177-1193. doi: 10.1038/s41562-024-01851-6 PMID: 37034728 Free PMC article. Updated. Preprint.
Polygenic risk score for problematic alcohol use predicts heavy drinking and alcohol use disorder symptoms in young adulthood after accounting for adolescent alcohol use and parental alcohol use disorder.
Wang FL, Hicks BM, Zhou H, Kranzler HR, Gelernter J, Zucker RA. Wang FL, et al. Among authors: zhou h. Drug Alcohol Depend. 2023 Jul 1;248:109909. doi: 10.1016/j.drugalcdep.2023.109909. Epub 2023 Apr 29. Drug Alcohol Depend. 2023. PMID: 37163864 Free PMC article.
Genetic Underpinnings of the Transition From Alcohol Consumption to Alcohol Use Disorder: Shared and Unique Genetic Architectures in a Cross-Ancestry Sample.
Kember RL, Vickers-Smith R, Zhou H, Xu H, Jennings M, Dao C, Davis L, Sanchez-Roige S, Justice AC, Gelernter J, Vujkovic M, Kranzler HR. Kember RL, et al. Among authors: zhou h. Am J Psychiatry. 2023 Aug 1;180(8):584-593. doi: 10.1176/appi.ajp.21090892. Epub 2023 Jun 7. Am J Psychiatry. 2023. PMID: 37282553 Free PMC article.
Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders.
Koller D, Mitjans M, Kouakou M, Friligkou E, Cabrera-Mendoza B, Deak JD, Llonga N, Pathak GA, Stiltner B, Løkhammer S, Levey DF, Zhou H, Hatoum AS, Kember RL, Kranzler HR, Stein MB, Corominas R, Demontis D, Artigas MS, Ramos-Quiroga JA, Gelernter J, Ribasés M, Cormand B, Polimanti R. Koller D, et al. Among authors: zhou h. Psychiatry Res. 2024 Mar;333:115758. doi: 10.1016/j.psychres.2024.115758. Epub 2024 Feb 3. Psychiatry Res. 2024. PMID: 38335780 Free article.
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