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Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFβ1 and IL-27.
Riehl DR, Sharma A, Roewe J, Murke F, Ruppert C, Eming SA, Bopp T, Kleinert H, Radsak MP, Colucci G, Subramaniam S, Reinhardt C, Giebel B, Prinz I, Guenther A, Strand D, Gunzer M, Waisman A, Ward PA, Ruf W, Schäfer K, Bosmann M. Riehl DR, et al. Among authors: schafer k. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2215421120. doi: 10.1073/pnas.2215421120. Epub 2023 Sep 27. Proc Natl Acad Sci U S A. 2023. PMID: 37756334 Free PMC article.
Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction.
Karbach SH, Schönfelder T, Brandão I, Wilms E, Hörmann N, Jäckel S, Schüler R, Finger S, Knorr M, Lagrange J, Brandt M, Waisman A, Kossmann S, Schäfer K, Münzel T, Reinhardt C, Wenzel P. Karbach SH, et al. Among authors: schafer k. J Am Heart Assoc. 2016 Aug 30;5(9):e003698. doi: 10.1161/JAHA.116.003698. J Am Heart Assoc. 2016. PMID: 27577581 Free PMC article.
T Cell-Derived IL-17A Induces Vascular Dysfunction via Perivascular Fibrosis Formation and Dysregulation of ·NO/cGMP Signaling.
Schüler R, Efentakis P, Wild J, Lagrange J, Garlapati V, Molitor M, Kossmann S, Oelze M, Stamm P, Li H, Schäfer K, Münzel T, Daiber A, Waisman A, Wenzel P, Karbach SH. Schüler R, et al. Among authors: schafer k. Oxid Med Cell Longev. 2019 Jul 18;2019:6721531. doi: 10.1155/2019/6721531. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31396305 Free PMC article.
Activated Endothelial TGFβ1 Signaling Promotes Venous Thrombus Nonresolution in Mice Via Endothelin-1: Potential Role for Chronic Thromboembolic Pulmonary Hypertension.
Bochenek ML, Leidinger C, Rosinus NS, Gogiraju R, Guth S, Hobohm L, Jurk K, Mayer E, Münzel T, Lankeit M, Bosmann M, Konstantinides S, Schäfer K. Bochenek ML, et al. Among authors: schafer k. Circ Res. 2020 Jan 17;126(2):162-181. doi: 10.1161/CIRCRESAHA.119.315259. Epub 2019 Nov 21. Circ Res. 2020. PMID: 31747868 Free PMC article.
The gut microbiota instructs the hepatic endothelial cell transcriptome.
Formes H, Bernardes JP, Mann A, Bayer F, Pontarollo G, Kiouptsi K, Schäfer K, Attig S, Nikolova T, Hofmann TG, Schattenberg JM, Todorov H, Gerber S, Rosenstiel P, Bopp T, Sommer F, Reinhardt C. Formes H, et al. Among authors: schafer k. iScience. 2021 Sep 10;24(10):103092. doi: 10.1016/j.isci.2021.103092. eCollection 2021 Oct 22. iScience. 2021. PMID: 34622147 Free PMC article.
Endothelial PTP1B Deletion Promotes VWF Exocytosis and Venous Thromboinflammation.
Zifkos K, Bochenek ML, Gogiraju R, Robert S, Pedrosa D, Kiouptsi K, Moiko K, Wagner M, Mahfoud F, Poncelet P, Münzel T, Ruf W, Reinhardt C, Panicot-Dubois L, Dubois C, Schäfer K. Zifkos K, et al. Among authors: schafer k. Circ Res. 2024 May 10;134(10):e93-e111. doi: 10.1161/CIRCRESAHA.124.324214. Epub 2024 Apr 2. Circ Res. 2024. PMID: 38563147 Free article.
930 results