NLRC5 deficiency ameliorates diabetic nephropathy through alleviating inflammation.
Luan P, Zhuang J, Zou J, Li H, Shuai P, Xu X, Zhao Y, Kou W, Ji S, Peng A, Xu Y, Su Q, Jian W, Peng W.
Luan P, et al. Among authors: peng w, peng a.
FASEB J. 2018 Feb;32(2):1070-1084. doi: 10.1096/fj.201700511RR. Epub 2018 Jan 3.
FASEB J. 2018.
PMID: 29070585
Taken together, NLRC5 promotes inflammation and fibrosis during DN progression partly through the effects on NF-kappaB and TGF-beta/Smad pathways. NLRC5 may, therefore, be a promising therapeutic target for DN treatment.-Luan, P., Zhuang, J., Zou, J., Li, H., Shuai, P., Xu …
Taken together, NLRC5 promotes inflammation and fibrosis during DN progression partly through the effects on NF-kappaB and TGF-beta/Smad pat …