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Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.
Ghorbani P, Kim SY, Smith TKT, Minarrieta L, Robert-Gostlin V, Kilgour MK, Ilijevska M, Alecu I, Snider SA, Margison KD, Nunes JRC, Woo D, Pember C, O'Dwyer C, Ouellette J, Kotchetkov P, St-Pierre J, Bennett SAL, Lacoste B, Blais A, Nair MG, Fullerton MD. Ghorbani P, et al. PLoS Pathog. 2023 Sep 25;19(9):e1011658. doi: 10.1371/journal.ppat.1011658. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747879 Free PMC article.
Mitochondrial elongation impairs breast cancer metastasis.
Minarrieta L, Annis MG, Audet-Delage Y, Kuasne H, Pacis A, St-Louis C, Nowakowski A, Biondini M, Khacho M, Park M, Siegel PM, St-Pierre J. Minarrieta L, et al. Among authors: st pierre j. Sci Adv. 2024 Nov 8;10(45):eadm8212. doi: 10.1126/sciadv.adm8212. Epub 2024 Nov 6. Sci Adv. 2024. PMID: 39504368 Free PMC article.
Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non-Small Cell Lung Cancer.
Mirhadi S, Zhang W, Pham NA, Karimzadeh F, Pintilie M, Tong J, Taylor P, Krieger J, Pitcher B, Sykes J, Wybenga-Groot L, Fladd C, Xu J, Wang T, Cabanero M, Li M, Weiss J, Sakashita S, Zaslaver O, Yu M, Caudy AA, St-Pierre J, Hawkins C, Kislinger T, Liu G, Shepherd FA, Tsao MS, Moran MF. Mirhadi S, et al. Mol Cancer Res. 2023 Jan 3;21(1):36-50. doi: 10.1158/1541-7786.MCR-22-0163. Mol Cancer Res. 2023. PMID: 36214668 Free PMC article.
Metabolic Profiles Associated With Metformin Efficacy in Cancer.
Andrzejewski S, Siegel PM, St-Pierre J. Andrzejewski S, et al. Front Endocrinol (Lausanne). 2018 Aug 21;9:372. doi: 10.3389/fendo.2018.00372. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 30186229 Free PMC article. Review.
STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer.
Totten SP, Im YK, Cepeda Cañedo E, Najyb O, Nguyen A, Hébert S, Ahn R, Lewis K, Lebeau B, La Selva R, Sabourin V, Martínez C, Savage P, Kuasne H, Avizonis D, Santos Martínez N, Chabot C, Aguilar-Mahecha A, Goulet ML, Dankner M, Witcher M, Petrecca K, Basik M, Pollak M, Topisirovic I, Lin R, Siegel PM, Kleinman CL, Park M, St-Pierre J, Ursini-Siegel J. Totten SP, et al. Nat Commun. 2021 Jun 3;12(1):3299. doi: 10.1038/s41467-021-23396-2. Nat Commun. 2021. PMID: 34083537 Free PMC article.
306 results