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Spesolimab Efficacy and Safety in Patients with Moderate-to-Severe Palmoplantar Pustulosis: A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase IIb, Dose-Finding Study.
Burden AD, Bissonnette R, Navarini AA, Murakami M, Morita A, Haeufel T, Ye B, Baehner F, Terui T. Burden AD, et al. Among authors: navarini aa. Dermatol Ther (Heidelb). 2023 Oct;13(10):2279-2297. doi: 10.1007/s13555-023-01002-1. Epub 2023 Sep 20. Dermatol Ther (Heidelb). 2023. PMID: 37731086 Free PMC article.
Rare pathogenic variants in IL36RN underlie a spectrum of psoriasis-associated pustular phenotypes.
Setta-Kaffetzi N, Navarini AA, Patel VM, Pullabhatla V, Pink AE, Choon SE, Allen MA, Burden AD, Griffiths CE, Seyger MM, Kirby B, Trembath RC, Simpson MA, Smith CH, Capon F, Barker JN. Setta-Kaffetzi N, et al. Among authors: navarini aa. J Invest Dermatol. 2013 May;133(5):1366-9. doi: 10.1038/jid.2012.490. Epub 2013 Jan 10. J Invest Dermatol. 2013. PMID: 23303454 Free article. No abstract available.
European consensus statement on phenotypes of pustular psoriasis.
Navarini AA, Burden AD, Capon F, Mrowietz U, Puig L, Köks S, Kingo K, Smith C, Barker JN; ERASPEN Network. Navarini AA, et al. J Eur Acad Dermatol Venereol. 2017 Nov;31(11):1792-1799. doi: 10.1111/jdv.14386. Epub 2017 Aug 29. J Eur Acad Dermatol Venereol. 2017. PMID: 28585342 Free article. Review.
Clinical and genetic differences between pustular psoriasis subtypes.
Twelves S, Mostafa A, Dand N, Burri E, Farkas K, Wilson R, Cooper HL, Irvine AD, Oon HH, Kingo K, Köks S, Mrowietz U, Puig L, Reynolds N, Tan ES, Tanew A, Torz K, Trattner H, Valentine M, Wahie S, Warren RB, Wright A, Bata-Csörgő Z, Szell M, Griffiths CEM, Burden AD, Choon SE, Smith CH, Barker JN, Navarini AA, Capon F. Twelves S, et al. Among authors: navarini aa. J Allergy Clin Immunol. 2019 Mar;143(3):1021-1026. doi: 10.1016/j.jaci.2018.06.038. Epub 2018 Jul 21. J Allergy Clin Immunol. 2019. PMID: 30036598 Free PMC article.
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.
Petridis C, Navarini AA, Dand N, Saklatvala J, Baudry D, Duckworth M, Allen MH, Curtis CJ, Lee SH, Burden AD, Layton A, Bataille V, Pink AE; Acne Genetic Study Group; Carlavan I, Voegel JJ, Spector TD, Trembath RC, McGrath JA, Smith CH, Barker JN, Simpson MA. Petridis C, et al. Among authors: navarini aa. Nat Commun. 2018 Dec 12;9(1):5075. doi: 10.1038/s41467-018-07459-5. Nat Commun. 2018. PMID: 30542056 Free PMC article.
Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease.
Vergnano M, Mockenhaupt M, Benzian-Olsson N, Paulmann M, Grys K, Mahil SK, Chaloner C, Barbosa IA, August S, Burden AD, Choon SE, Cooper H, Navarini AA, Reynolds NJ, Wahie S, Warren RB, Wright A; APRICOT and PLUM study team; Huffmeier U, Baum P, Visvanathan S, Barker JN, Smith CH, Capon F. Vergnano M, et al. Among authors: navarini aa. Am J Hum Genet. 2020 Sep 3;107(3):539-543. doi: 10.1016/j.ajhg.2020.06.020. Epub 2020 Aug 5. Am J Hum Genet. 2020. PMID: 32758448 Free PMC article.
Association of Clinical and Demographic Factors With the Severity of Palmoplantar Pustulosis.
Benzian-Olsson N, Dand N, Chaloner C, Bata-Csorgo Z, Borroni R, Burden AD, Cooper HL, Cornelius V, Cro S, Dasandi T, Griffiths CEM, Kingo K, Koks S, Lachmann H, McAteer H, Meynell F, Mrowietz U, Parslew R, Patel P, Pink AE, Reynolds NJ, Tanew A, Torz K, Trattner H, Wahie S, Warren RB, Wright A, Barker JN, Navarini AA, Smith CH, Capon F; ERASPEN consortium and the APRICOT and PLUM study team. Benzian-Olsson N, et al. Among authors: navarini aa. JAMA Dermatol. 2020 Nov 1;156(11):1216-1222. doi: 10.1001/jamadermatol.2020.3275. JAMA Dermatol. 2020. PMID: 32936291 Free PMC article.
Study protocol of the global Effisayil 1 Phase II, multicentre, randomised, double-blind, placebo-controlled trial of spesolimab in patients with generalized pustular psoriasis presenting with an acute flare.
Choon SE, Lebwohl MG, Marrakchi S, Burden AD, Tsai TF, Morita A, Navarini AA, Zheng M, Xu J, Turki H, Rajeswari S, Deng H, Tetzlaff K, Thoma C, Bachelez H. Choon SE, et al. Among authors: navarini aa. BMJ Open. 2021 Mar 30;11(3):e043666. doi: 10.1136/bmjopen-2020-043666. BMJ Open. 2021. PMID: 33785490 Free PMC article.
Trial of Spesolimab for Generalized Pustular Psoriasis.
Bachelez H, Choon SE, Marrakchi S, Burden AD, Tsai TF, Morita A, Navarini AA, Zheng M, Xu J, Turki H, Anadkat MJ, Rajeswari S, Hua H, Vulcu SD, Hall D, Tetzlaff K, Thoma C, Lebwohl MG; Effisayil 1 Trial Investigators. Bachelez H, et al. Among authors: navarini aa. N Engl J Med. 2021 Dec 23;385(26):2431-2440. doi: 10.1056/NEJMoa2111563. N Engl J Med. 2021. PMID: 34936739 Free article. Clinical Trial.
Clinical Disease Measures in Generalized Pustular Psoriasis.
Burden AD, Choon SE, Gottlieb AB, Navarini AA, Warren RB. Burden AD, et al. Among authors: navarini aa. Am J Clin Dermatol. 2022 Jan;23(Suppl 1):39-50. doi: 10.1007/s40257-021-00653-0. Epub 2022 Jan 21. Am J Clin Dermatol. 2022. PMID: 35061231 Free PMC article. Review.
245 results