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Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and solid tumor microenvironment.
Wang Y, Drum DL, Sun R, Zhang Y, Chen F, Sun F, Dal E, Yu L, Jia J, Arya S, Jia L, Fan S, Isakoff SJ, Kehlmann AM, Dotti G, Liu F, Zheng H, Ferrone CR, Taghian AG, DeLeo AB, Ventin M, Cattaneo G, Li Y, Jounaidi Y, Huang P, Maccalli C, Zhang H, Wang C, Yang J, Boland GM, Sadreyev RI, Wong L, Ferrone S, Wang X. Wang Y, et al. Among authors: drum dl. Nat Commun. 2023 Sep 15;14(1):5727. doi: 10.1038/s41467-023-41282-x. Nat Commun. 2023. PMID: 37714830 Free PMC article.
Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and tumor microenvironment, overcoming multiple obstacles of CAR T therapy for solid tumors.
Wang Y, Drum DL, Sun R, Zhang Y, Yu L, Jia L, Isakoff SJ, Kehlmann AM, Dal AE, Dotti G, Zheng H, Ferrone CR, Taghian AG, DeLeo AB, Zhang H, Jounaidi Y, Fan S, Huang P, Wang C, Yang J, Boland GM, Sadreyev RI, Wong L, Ferrone S, Wang X. Wang Y, et al. Among authors: drum dl. Res Sq [Preprint]. 2023 Feb 21:rs.3.rs-2595410. doi: 10.21203/rs.3.rs-2595410/v1. Res Sq. 2023. Update in: Nat Commun. 2023 Sep 15;14(1):5727. doi: 10.1038/s41467-023-41282-x. PMID: 36865255 Free PMC article. Updated. Preprint.