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RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.
Krishnan R, Lapierre M, Gautreau B, Nixon KCJ, El Ghamrasni S, Patel PS, Hao J, Yerlici VT, Guturi KKN, St-Germain J, Mateo F, Saad A, Algouneh A, Earnshaw R, Shili D, Seitova A, Miller J, Khosraviani N, Penn A, Ho B, Sanchez O, Hande MP, Masson JY, Brown GW, Alaoui-Jamali M, Reynolds JJ, Arrowsmith C, Raught B, Pujana MA, Mekhail K, Stewart GS, Hakem A, Hakem R. Krishnan R, et al. Among authors: hakem r. Nucleic Acids Res. 2023 Oct 27;51(19):10484-10505. doi: 10.1093/nar/gkad733. Nucleic Acids Res. 2023. PMID: 37697435 Free PMC article.
Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity.
Krajewska M, You Z, Rong J, Kress C, Huang X, Yang J, Kyoda T, Leyva R, Banares S, Hu Y, Sze CH, Whalen MJ, Salmena L, Hakem R, Head BP, Reed JC, Krajewski S. Krajewska M, et al. Among authors: hakem r. PLoS One. 2011;6(9):e24341. doi: 10.1371/journal.pone.0024341. Epub 2011 Sep 16. PLoS One. 2011. PMID: 21957448 Free PMC article.
RIP3 mediates the embryonic lethality of caspase-8-deficient mice.
Kaiser WJ, Upton JW, Long AB, Livingston-Rosanoff D, Daley-Bauer LP, Hakem R, Caspary T, Mocarski ES. Kaiser WJ, et al. Among authors: hakem r. Nature. 2011 Mar 17;471(7338):368-72. doi: 10.1038/nature09857. Epub 2011 Mar 2. Nature. 2011. PMID: 21368762 Free PMC article.
Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation.
Luk CT, Chan CK, Chiu F, Shi SY, Misra PS, Li YZ, Pollock-Tahiri E, Schroer SA, Desai HR, Sivasubramaniyam T, Cai EP, Krishnamurthy M, Han DJ, Chowdhury A, Aslam R, Yuen DA, Hakem A, Hakem R, Woo M. Luk CT, et al. Among authors: hakem r. Diabetes. 2023 Dec 1;72(12):1751-1765. doi: 10.2337/db22-1033. Diabetes. 2023. PMID: 37699387
Caspase-12 compensates for lack of caspase-2 and caspase-3 in female germ cells.
Takai Y, Matikainen T, Jurisicova A, Kim MR, Trbovich AM, Fujita E, Nakagawa T, Lemmers B, Flavell RA, Hakem R, Momoi T, Yuan J, Tilly JL, Perez GI. Takai Y, et al. Among authors: hakem r. Apoptosis. 2007 Apr;12(4):791-800. doi: 10.1007/s10495-006-0022-z. Apoptosis. 2007. PMID: 17245644
117 results