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Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir.
Duan Y, Zhou H, Liu X, Iketani S, Lin M, Zhang X, Bian Q, Wang H, Sun H, Hong SJ, Culbertson B, Mohri H, Luck MI, Zhu Y, Liu X, Lu Y, Yang X, Yang K, Sabo Y, Chavez A, Goff SP, Rao Z, Ho DD, Yang H. Duan Y, et al. Among authors: iketani s. Nature. 2023 Oct;622(7982):376-382. doi: 10.1038/s41586-023-06609-0. Epub 2023 Sep 11. Nature. 2023. PMID: 37696289
A simplified cell-based assay to identify coronavirus 3CL protease inhibitors.
Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Nair MS, Huang Y, Tay NES, Rovis T, Yang HW, Stockwell BR, Ho DD, Chavez A. Resnick SJ, et al. Among authors: iketani s. bioRxiv [Preprint]. 2020 Aug 29:2020.08.29.272864. doi: 10.1101/2020.08.29.272864. bioRxiv. 2020. PMID: 32869020 Free PMC article. Preprint.
Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7.
Wang P, Nair MS, Liu L, Iketani S, Luo Y, Guo Y, Wang M, Yu J, Zhang B, Kwong PD, Graham BS, Mascola JR, Chang JY, Yin MT, Sobieszczyk M, Kyratsous CA, Shapiro L, Sheng Z, Huang Y, Ho DD. Wang P, et al. Among authors: iketani s. bioRxiv [Preprint]. 2021 Feb 12:2021.01.25.428137. doi: 10.1101/2021.01.25.428137. bioRxiv. 2021. Update in: Nature. 2021 May;593(7857):130-135. doi: 10.1038/s41586-021-03398-2. PMID: 33532778 Free PMC article. Updated. Preprint.
Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7.
Wang P, Nair MS, Liu L, Iketani S, Luo Y, Guo Y, Wang M, Yu J, Zhang B, Kwong PD, Graham BS, Mascola JR, Chang JY, Yin MT, Sobieszczyk M, Kyratsous CA, Shapiro L, Sheng Z, Huang Y, Ho DD. Wang P, et al. Among authors: iketani s. Nature. 2021 May;593(7857):130-135. doi: 10.1038/s41586-021-03398-2. Epub 2021 Mar 8. Nature. 2021. PMID: 33684923
Inhibitors of Coronavirus 3CL Proteases Protect Cells from Protease-Mediated Cytotoxicity.
Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Lin FY, Nair MS, Huang Y, Lee S, Tay NES, Rovis T, Yang HW, Xing L, Stockwell BR, Ho DD, Chavez A. Resnick SJ, et al. Among authors: iketani s. J Virol. 2021 Jun 24;95(14):e0237420. doi: 10.1128/JVI.02374-20. Epub 2021 Jun 24. J Virol. 2021. PMID: 33910954 Free PMC article.
A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses.
Wang P, Casner RG, Nair MS, Yu J, Guo Y, Wang M, Chan JF, Cerutti G, Iketani S, Liu L, Sheng Z, Chen Z, Yuen KY, Kwong PD, Huang Y, Shapiro L, Ho DD. Wang P, et al. Among authors: iketani s. bioRxiv [Preprint]. 2021 Oct 14:2021.10.13.464307. doi: 10.1101/2021.10.13.464307. bioRxiv. 2021. Update in: Emerg Microbes Infect. 2022 Dec;11(1):147-157. doi: 10.1080/22221751.2021.2011623. PMID: 34671769 Free PMC article. Updated. Preprint.
56 results