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115 results

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Page 1
Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders.
Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JR, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegoviç E, Babic D, Bacanu SA, Baker DG, Batzler A, Beckham JC, Belangero S, Benjet C, Bergner C, Bierer LM, Biernacka JM, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Brandolino A, Breen G, Bressan RA, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Bækvad-Hansen M, Børglum AD, Børte S, Cahn L, Calabrese JR, Caldas-de-Almeida JM, Chatzinakos C, Cheema S, Clouston SAP, Colodro-Conde L, Coombes BJ, Cruz-Fuentes CS, Dale AM, Dalvie S, Davis LK, Deckert J, Delahanty DL, Dennis MF, deRoon-Cassini T, Desarnaud F, DiPietro CP, Disner SG, Docherty AR, Domschke K, Dyb G, Kulenovic AD, Edenberg HJ, Evans A, Fabbri C, Fani N, Farrer LA, Feder A, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Gelernter J, Geuze E, Gillespie CF, Goci A, Goleva SB, Gordon SD, Grasser LR, Guindalini C, Haas M, Hagenaars S, Hauser MA, Heath AC, Hemmings SM, Hesselbrock V, Hickie IB, Hogan K, Hougaard DM, Huang H, Huckins LM, Hveem K, Jakovljevic M, Javanbakht A, Jenkins GD, Johnson J, Jones … See abstract for full author list ➔ Nievergelt CM, et al. Among authors: lehto k. medRxiv [Preprint]. 2023 Sep 2:2023.08.31.23294915. doi: 10.1101/2023.08.31.23294915. medRxiv. 2023. PMID: 37693460 Free PMC article. Preprint.
Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study.
Magnúsdóttir I, Lovik A, Unnarsdóttir AB, McCartney D, Ask H, Kõiv K, Christoffersen LAN, Johnson SU, Hauksdóttir A, Fawns-Ritchie C, Helenius D, González-Hijón J, Lu L, Ebrahimi OV, Hoffart A, Porteous DJ, Fang F, Jakobsdóttir J, Lehto K, Andreassen OA, Pedersen OBV, Aspelund T, Valdimarsdóttir UA; COVIDMENT Collaboration. Magnúsdóttir I, et al. Among authors: lehto k. Lancet Public Health. 2022 May;7(5):e406-e416. doi: 10.1016/S2468-2667(22)00042-1. Epub 2022 Mar 14. Lancet Public Health. 2022. PMID: 35298894 Free PMC article.
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.
Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JRI, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegoviç E, Babić D, Bacanu SA, Baker DG, Batzler A, Beckham JC, Belangero S, Benjet C, Bergner C, Bierer LM, Biernacka JM, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Brandolino A, Breen G, Bressan RA, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Bækvad-Hansen M, Børglum AD, Børte S, Cahn L, Calabrese JR, Caldas-de-Almeida JM, Chatzinakos C, Cheema S, Clouston SAP, Colodro-Conde L, Coombes BJ, Cruz-Fuentes CS, Dale AM, Dalvie S, Davis LK, Deckert J, Delahanty DL, Dennis MF, Desarnaud F, DiPietro CP, Disner SG, Docherty AR, Domschke K, Dyb G, Kulenović AD, Edenberg HJ, Evans A, Fabbri C, Fani N, Farrer LA, Feder A, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Gelernter J, Geuze E, Gillespie CF, Goleva SB, Gordon SD, Goçi A, Grasser LR, Guindalini C, Haas M, Hagenaars S, Hauser MA, Heath AC, Hemmings SMJ, Hesselbrock V, Hickie IB, Hogan K, Hougaard DM, Huang H, Huckins LM, Hveem K, Jakovljević M, Javanbakht A, Jenkins GD, Johnson J, Jones I, Jovanovic T, … See abstract for full author list ➔ Nievergelt CM, et al. Among authors: lehto k. Nat Genet. 2024 May;56(5):792-808. doi: 10.1038/s41588-024-01707-9. Epub 2024 Apr 18. Nat Genet. 2024. PMID: 38637617 Free PMC article.
Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood.
Daskalakis NP, Iatrou A, Chatzinakos C, Jajoo A, Snijders C, Wylie D, DiPietro CP, Tsatsani I, Chen CY, Pernia CD, Soliva-Estruch M, Arasappan D, Bharadwaj RA, Collado-Torres L, Wuchty S, Alvarez VE, Dammer EB, Deep-Soboslay A, Duong DM, Eagles N, Huber BR, Huuki L, Holstein VL, Logue MW, Lugenbühl JF, Maihofer AX, Miller MW, Nievergelt CM, Pertea G, Ross D, Sendi MSE, Sun BB, Tao R, Tooke J, Wolf EJ, Zeier Z; PTSD Working Group of Psychiatric Genomics Consortium**; Berretta S, Champagne FA, Hyde T, Seyfried NT, Shin JH, Weinberger DR, Nemeroff CB, Kleinman JE, Ressler KJ; PTSD Working Group of Psychiatric Genomics Consortium. Daskalakis NP, et al. Science. 2024 May 24;384(6698):eadh3707. doi: 10.1126/science.adh3707. Epub 2024 May 24. Science. 2024. PMID: 38781393
Neandertal introgression partitions the genetic landscape of neuropsychiatric disorders and associated behavioral phenotypes.
Dannemann M, Milaneschi Y, Yermakovich D, Stiglbauer V, Kariis HM, Krebs K, Friese MA, Otte C; Estonian Biobank Research Team; Lehto K, Penninx BWJH, Kelso J, Gold SM. Dannemann M, et al. Among authors: lehto k. Transl Psychiatry. 2022 Oct 5;12(1):433. doi: 10.1038/s41398-022-02196-2. Transl Psychiatry. 2022. PMID: 36198681 Free PMC article.
COVID-19 illness severity and 2-year prevalence of physical symptoms: an observational study in Iceland, Sweden, Norway and Denmark.
Shen Q, Joyce EE, Ebrahimi OV, Didriksen M, Lovik A, Sævarsdóttir KS, Magnúsdóttir I, Mikkelsen DH, Unnarsdóttir AB, Hauksdóttir A, Hoffart A, Kähler AK, Thórdardóttir EB, Eythórsson E, Frans EM, Tómasson G, Ask H, Hardardóttir H, Jakobsdóttir J, Lehto K, Lu L, Andreassen OA, Sullivan PF, Pálsson R, Erikstrup C, Ostrowski SR, Werge T, Aspelund T, Pedersen OBV, Johnson SU, Fang F, Valdimarsdóttir UA. Shen Q, et al. Among authors: lehto k. Lancet Reg Health Eur. 2023 Oct 27;35:100756. doi: 10.1016/j.lanepe.2023.100756. eCollection 2023 Dec. Lancet Reg Health Eur. 2023. PMID: 38115966 Free PMC article.
Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations.
Unnarsdóttir AB, Lovik A, Fawns-Ritchie C, Ask H, Kõiv K, Hagen K, Didriksen M, Christoffersen LAN, Garðarsson AB, McIntosh A, Kähler AK, Campbell A, Hauksdóttir A, Erikstrup C, Mikkelsen DH, Altschul D, Thordardottir EB, Frans EM, Kvale G, Tómasson G, Kariis HM, Jónsdóttir HL, Rúnarsdóttir H, Magnúsdóttir I, Eid J, Jakobsdóttir J, Nielsen KR, Kaspersen KA, Milani L, Trogstad LS, Yi L, Bruun MT, Sullivan PF, Magnus PM, Shen Q, Nesvåg R, Brandlistuen RE, Mägi R, Ostrowski SR, Løkhammer S, Solem S, Reichborn-Kjennerud T, Hansen TF, Werge T, Aspelund T, Porteous DJ, Fang F, Lehto K, Andreassen OA, Pedersen OBV, Hellard SL, Valdimarsdóttir UA. Unnarsdóttir AB, et al. Among authors: lehto k. Int J Epidemiol. 2022 Jun 13;51(3):e108-e122. doi: 10.1093/ije/dyab234. Int J Epidemiol. 2022. PMID: 35020900 Free PMC article. No abstract available.
Socio-demographic and genetic risk factors for drug adherence and persistence across 5 common medication classes.
Cordioli M, Corbetta A, Kariis HM, Jukarainen S, Vartiainen P, Kiiskinen T, Ferro M; FinnGen; Estonian Biobank Research Team; Perola M, Niemi M, Ripatti S, Lehto K, Milani L, Ganna A. Cordioli M, et al. Among authors: lehto k. Nat Commun. 2024 Oct 23;15(1):9156. doi: 10.1038/s41467-024-53556-z. Nat Commun. 2024. PMID: 39443518 Free PMC article.
Mental illness and COVID-19 vaccination: a multinational investigation of observational & register-based data.
Barker MM, Kõiv K, Magnúsdóttir I, Milbourn H, Wang B, Du X, Murphy G, Herweijer E, Gísladóttir EU, Li H, Lovik A, Kähler AK, Campbell A, Feychting M, Hauksdóttir A, Joyce EE, Thordardottir EB, Frans EM, Hoffart A, Mägi R, Tómasson G, Ásbjörnsdóttir K, Jakobsdóttir J, Andreassen OA, Sullivan PF, Johnson SU, Aspelund T, Brandlistuen RE, Ask H, McCartney DL, Ebrahimi OV, Lehto K, Valdimarsdóttir UA, Nyberg F, Fang F. Barker MM, et al. Among authors: lehto k. Nat Commun. 2024 Sep 26;15(1):8124. doi: 10.1038/s41467-024-52342-1. Nat Commun. 2024. PMID: 39327436 Free PMC article.
Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts.
Adams MJ, Thorp JG, Jermy BS, Kwong ASF, Kõiv K, Grotzinger AD, Nivard MG, Marshall S, Milaneschi Y, Baune BT, Müller-Myhsok B, Penninx BWJH, Boomsma DI, Levinson DF, Breen G, Pistis G, Grabe HJ, Tiemeier H, Berger K, Rietschel M, Magnusson PK, Uher R, Hamilton SP, Lucae S, Lehto K, Li QS, Byrne EM, Hickie IB, Martin NG, Medland SE, Wray NR, Tucker-Drob EM; Estonian Biobank Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Lewis CM, McIntosh AM, Derks EM. Adams MJ, et al. Among authors: lehto k. Psychol Med. 2024 Sep;54(12):3459-3468. doi: 10.1017/S0033291724001880. Epub 2024 Sep 26. Psychol Med. 2024. PMID: 39324397 Free PMC article.
115 results