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Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells.
Yuan L, Ma X, Yang Y, Qu Y, Li X, Zhu X, Ma W, Duan J, Xue J, Yang H, Huang JW, Yi S, Zhang M, Cai N, Zhang L, Ding Q, Lai K, Liu C, Zhang L, Liu X, Yao Y, Zhou S, Li X, Shen P, Chang Q, Malwal SR, He Y, Li W, Chen C, Chen CC, Oldfield E, Guo RT, Zhang Y. Yuan L, et al. Among authors: ma w, ma x. Nature. 2023 Sep;621(7980):840-848. doi: 10.1038/s41586-023-06525-3. Epub 2023 Sep 6. Nature. 2023. PMID: 37674084 Free PMC article.
A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated Vγ9Vδ2 T Cell Activation.
Yang Y, Li L, Yuan L, Zhou X, Duan J, Xiao H, Cai N, Han S, Ma X, Liu W, Chen CC, Wang L, Li X, Chen J, Kang N, Chen J, Shen Z, Malwal SR, Liu W, Shi Y, Oldfield E, Guo RT, Zhang Y. Yang Y, et al. Among authors: ma x. Immunity. 2019 Apr 16;50(4):1043-1053.e5. doi: 10.1016/j.immuni.2019.02.016. Epub 2019 Mar 19. Immunity. 2019. PMID: 30902636 Free article.
TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet's disease.
Zhang M, Kang N, Yu X, Zhang X, Duan Q, Ma X, Zhao Q, Wang Z, Wang X, Liu Y, Zhang Y, Zhu C, Gao R, Min X, Li C, Jin J, Cao Q, Liu R, Bai X, Yang H, Zhao L, Liu J, Chen H, Zhang Y, Liu W, Zheng W. Zhang M, et al. Among authors: ma x. Nat Commun. 2024 Oct 26;15(1):9261. doi: 10.1038/s41467-024-53528-3. Nat Commun. 2024. PMID: 39461948 Free PMC article.
Farnesyl pyrophosphate is a new danger signal inducing acute cell death.
Chen J, Zhang X, Li L, Ma X, Yang C, Liu Z, Li C, Fernandez-Cabezudo MJ, Al-Ramadi BK, Wu C, Huang W, Zhang Y, Zhang Y, Liu W. Chen J, et al. Among authors: ma x. PLoS Biol. 2021 Apr 26;19(4):e3001134. doi: 10.1371/journal.pbio.3001134. eCollection 2021 Apr. PLoS Biol. 2021. PMID: 33901180 Free PMC article.
Correction: Farnesyl pyrophosphate is a new danger signal inducing acute cell death.
Chen J, Zhang X, Li L, Ma X, Yang C, Liu Z, Li C, Fernandez-Cabezudo MJ, Al-Ramadi BK, Wu C, Huang W, Zhang Y, Zhang Y, Liu W. Chen J, et al. Among authors: ma x. PLoS Biol. 2023 Nov 15;21(11):e3002414. doi: 10.1371/journal.pbio.3002414. eCollection 2023 Nov. PLoS Biol. 2023. PMID: 37967298 Free PMC article.
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