Chen CXQ - Search Results

1

MerTK is a mediator of alpha-synuclein fibril uptake by human microglia.

Dorion MF, Yaqubi M, Senkevich K, Kieran NW, MacDonald A, Chen CXQ, Luo W, Wallis A, Shlaifer I, Hall JA, Dudley RWR, Glass IA; Birth Defects Research Laboratory; Stratton JA, Fon EA, Bartels T, Antel JP, Gan-Or Z, Durcan TM, Healy LM. Dorion MF, et al. Among authors: chen cxq. Brain. 2024 Feb 1;147(2):427-443. doi: 10.1093/brain/awad298. Brain. 2024. PMID: 37671615 Free PMC article.

2

Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels.

Joch M, Ase AR, Chen CX, MacDonald PA, Kontogiannea M, Corera AT, Brice A, Séguéla P, Fon EA. Joch M, et al. Mol Biol Cell. 2007 Aug;18(8):3105-18. doi: 10.1091/mbc.e05-11-1027. Epub 2007 Jun 6. Mol Biol Cell. 2007. PMID: 17553932 Free PMC article.

3

SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.

Trempe JF, Chen CX, Grenier K, Camacho EM, Kozlov G, McPherson PS, Gehring K, Fon EA. Trempe JF, et al. Mol Cell. 2009 Dec 25;36(6):1034-47. doi: 10.1016/j.molcel.2009.11.021. Mol Cell. 2009. PMID: 20064468 Free article.

4

Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control.

McLelland GL, Soubannier V, Chen CX, McBride HM, Fon EA. McLelland GL, et al. EMBO J. 2014 Feb 18;33(4):282-95. doi: 10.1002/embj.201385902. Epub 2014 Jan 20. EMBO J. 2014. PMID: 24446486 Free PMC article.

5

Open Science Meets Stem Cells: A New Drug Discovery Approach for Neurodegenerative Disorders.

Han C, Chaineau M, Chen CX, Beitel LK, Durcan TM. Han C, et al. Front Neurosci. 2018 Feb 6;12:47. doi: 10.3389/fnins.2018.00047. eCollection 2018. Front Neurosci. 2018. PMID: 29467610 Free PMC article. Review.

6

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.

McLelland GL, Goiran T, Yi W, Dorval G, Chen CX, Lauinger ND, Krahn AI, Valimehr S, Rakovic A, Rouiller I, Durcan TM, Trempe JF, Fon EA. McLelland GL, et al. Elife. 2018 Apr 20;7:e32866. doi: 10.7554/eLife.32866. Elife. 2018. PMID: 29676259 Free PMC article.

7

Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72.

Laflamme C, McKeever PM, Kumar R, Schwartz J, Kolahdouzan M, Chen CX, You Z, Benaliouad F, Gileadi O, McBride HM, Durcan TM, Edwards AM, Healy LM, Robertson J, McPherson PS. Laflamme C, et al. Elife. 2019 Oct 15;8:e48363. doi: 10.7554/eLife.48363. Elife. 2019. PMID: 31612854 Free PMC article.

8

Nanotherapeutic Modulation of Human Neural Cells and Glioblastoma in Organoids and Monocultures.

Zhang I, Lépine P, Han C, Lacalle-Aurioles M, Chen CX, Haag R, Durcan TM, Maysinger D. Zhang I, et al. Cells. 2020 Nov 7;9(11):2434. doi: 10.3390/cells9112434. Cells. 2020. PMID: 33171886 Free PMC article.

9

A Multistep Workflow to Evaluate Newly Generated iPSCs and Their Ability to Generate Different Cell Types.

Chen CX, Abdian N, Maussion G, Thomas RA, Demirova I, Cai E, Tabatabaei M, Beitel LK, Karamchandani J, Fon EA, Durcan TM. Chen CX, et al. Methods Protoc. 2021 Jul 19;4(3):50. doi: 10.3390/mps4030050. Methods Protoc. 2021. PMID: 34287353 Free PMC article.

10

A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis.

Deneault E, Chaineau M, Nicouleau M, Castellanos Montiel MJ, Franco Flores AK, Haghi G, Chen CX, Abdian N, Shlaifer I, Beitel LK, Durcan TM. Deneault E, et al. Methods. 2022 Jul;203:297-310. doi: 10.1016/j.ymeth.2021.09.002. Epub 2021 Sep 6. Methods. 2022. PMID: 34500068 Free article.

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