Zagorulya M - Search Results

1

Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2.

Horton BL, D'Souza AD, Zagorulya M, McCreery CV, Abhiraman GC, Picton L, Sheen A, Agarwal Y, Momin N, Wittrup KD, White FM, Garcia KC, Spranger S. Horton BL, et al. Among authors: zagorulya m. JCI Insight. 2023 Oct 9;8(19):e172728. doi: 10.1172/jci.insight.172728. JCI Insight. 2023. PMID: 37669107 Free PMC article.

2

Lack of CD8⁺ T cell effector differentiation during priming mediates checkpoint blockade resistance in non-small cell lung cancer.

Horton BL, Morgan DM, Momin N, Zagorulya M, Torres-Mejia E, Bhandarkar V, Wittrup KD, Love JC, Spranger S. Horton BL, et al. Among authors: zagorulya m. Sci Immunol. 2021 Oct 29;6(64):eabi8800. doi: 10.1126/sciimmunol.abi8800. Epub 2021 Oct 29. Sci Immunol. 2021. PMID: 34714687 Free PMC article.

3

Once upon a prime: DCs shape cancer immunity.

Zagorulya M, Spranger S. Zagorulya M, et al. Trends Cancer. 2023 Feb;9(2):172-184. doi: 10.1016/j.trecan.2022.10.006. Epub 2022 Nov 7. Trends Cancer. 2023. PMID: 36357313 Free PMC article. Review.

4

Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer.

Zagorulya M, Yim L, Morgan DM, Edwards A, Torres-Mejia E, Momin N, McCreery CV, Zamora IL, Horton BL, Fox JG, Wittrup KD, Love JC, Spranger S. Zagorulya M, et al. Immunity. 2023 Feb 14;56(2):386-405.e10. doi: 10.1016/j.immuni.2023.01.010. Epub 2023 Feb 2. Immunity. 2023. PMID: 36736322 Free PMC article.

5

Impact of anatomic site on antigen-presenting cells in cancer.

Zagorulya M, Duong E, Spranger S. Zagorulya M, et al. J Immunother Cancer. 2020 Oct;8(2):e001204. doi: 10.1136/jitc-2020-001204. J Immunother Cancer. 2020. PMID: 33020244 Free PMC article. Review.

6

Direct and Indirect Regulators of Epithelial-Mesenchymal Transition-Mediated Immunosuppression in Breast Carcinomas.

Dongre A, Rashidian M, Eaton EN, Reinhardt F, Thiru P, Zagorulya M, Nepal S, Banaz T, Martner A, Spranger S, Weinberg RA. Dongre A, et al. Among authors: zagorulya m. Cancer Discov. 2021 May;11(5):1286-1305. doi: 10.1158/2159-8290.CD-20-0603. Epub 2020 Dec 16. Cancer Discov. 2021. PMID: 33328216 Free PMC article.

7

Increased demand for NAD⁺ relative to ATP drives aerobic glycolysis.

Luengo A, Li Z, Gui DY, Sullivan LB, Zagorulya M, Do BT, Ferreira R, Naamati A, Ali A, Lewis CA, Thomas CJ, Spranger S, Matheson NJ, Vander Heiden MG. Luengo A, et al. Among authors: zagorulya m. Mol Cell. 2021 Feb 18;81(4):691-707.e6. doi: 10.1016/j.molcel.2020.12.012. Epub 2020 Dec 30. Mol Cell. 2021. PMID: 33382985 Free PMC article.

8

MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.

Puttick C, Jones TP, Leung MM, Galvez-Cancino F, Liu J, Varas-Godoy M, Rowan A, Pich O, Martinez-Ruiz C, Bentham R, Dijkstra KK, Black JRM, Rosenthal R, Kanu N, Litchfield K, Salgado R, Moore DA, Van Loo P, Jamal-Hanjani M, Quezada SA; TRACERx Consortium; Swanton C, McGranahan N. Puttick C, et al. Nat Genet. 2024 Oct;56(10):2121-2131. doi: 10.1038/s41588-024-01883-8. Epub 2024 Oct 2. Nat Genet. 2024. PMID: 39358601 Free PMC article.

9

Expansion of tumor-reactive CD8⁺ T cell clonotypes occurs in the spleen in response to immune checkpoint blockade.

Morgan DM, Horton BL, Bhandarkar V, Van R, Dinter T, Zagorulya M, Love JC, Spranger S. Morgan DM, et al. Among authors: zagorulya m. Sci Immunol. 2024 Sep 13;9(99):eadi3487. doi: 10.1126/sciimmunol.adi3487. Epub 2024 Sep 13. Sci Immunol. 2024. PMID: 39270006 Free PMC article.

10

A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.

Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. Among authors: zagorulya m. EMBO J. 2023 Feb 1;42(3):e113326. doi: 10.15252/embj.2022113326. EMBO J. 2023. PMID: 36722290 Free PMC article.

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