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Page 1
Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control.
Gurzeler LA, Link M, Ibig Y, Schmidt I, Galuba O, Schoenbett J, Gasser-Didierlaurant C, Parker CN, Mao X, Bitsch F, Schirle M, Couttet P, Sigoillot F, Ziegelmüller J, Uldry AC, Teodorowicz W, Schmiedeberg N, Mühlemann O, Reinhardt J. Gurzeler LA, et al. Among authors: couttet p. Cell Rep. 2023 Sep 26;42(9):113056. doi: 10.1016/j.celrep.2023.113056. Epub 2023 Aug 30. Cell Rep. 2023. PMID: 37651229 Free article.
Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control.
Gurzeler LA, Link M, Ibig Y, Schmidt I, Galuba O, Schoenbett J, Gasser-Didierlaurant C, Parker CN, Mao X, Bitsch F, Schirle M, Couttet P, Sigoillot F, Ziegelmüller J, Uldry AC, Teodorowicz W, Schmiedeberg N, Mühlemann O, Reinhardt J. Gurzeler LA, et al. Among authors: couttet p. Cell Rep. 2023 Sep 26;42(9):113159. doi: 10.1016/j.celrep.2023.113159. Epub 2023 Sep 13. Cell Rep. 2023. PMID: 37708027 Free article. No abstract available.
Identification of marker genes to monitor residual iPSCs in iPSC-derived products.
Lemmens M, Perner J, Potgeter L, Zogg M, Thiruchelvam S, Müller M, Doll T, Werner A, Gilbart Y, Couttet P, Martus HJ, Libertini S. Lemmens M, et al. Among authors: couttet p. Cytotherapy. 2023 Jan;25(1):59-67. doi: 10.1016/j.jcyt.2022.09.010. Epub 2022 Oct 29. Cytotherapy. 2023. PMID: 36319564
Methodological considerations for measuring biofluid-based microRNA biomarkers.
Chorley BN, Atabakhsh E, Doran G, Gautier JC, Ellinger-Ziegelbauer H, Jackson D, Sharapova T, Yuen PST, Church RJ, Couttet P, Froetschl R, McDuffie J, Martinez V, Pande P, Peel L, Rafferty C, Simutis FJ, Harrill AH. Chorley BN, et al. Among authors: couttet p. Crit Rev Toxicol. 2021 Mar;51(3):264-282. doi: 10.1080/10408444.2021.1907530. Epub 2021 May 26. Crit Rev Toxicol. 2021. PMID: 34038674 Free PMC article.
Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4.
Fairhurst RA, Knoepfel T, Buschmann N, Leblanc C, Mah R, Todorov M, Nimsgern P, Ripoche S, Niklaus M, Warin N, Luu VH, Madoerin M, Wirth J, Graus-Porta D, Weiss A, Kiffe M, Wartmann M, Kinyamu-Akunda J, Sterker D, Stamm C, Adler F, Buhles A, Schadt H, Couttet P, Blank J, Galuba I, Trappe J, Voshol J, Ostermann N, Zou C, Berghausen J, Del Rio Espinola A, Jahnke W, Furet P. Fairhurst RA, et al. Among authors: couttet p. J Med Chem. 2020 Nov 12;63(21):12542-12573. doi: 10.1021/acs.jmedchem.0c01019. Epub 2020 Oct 1. J Med Chem. 2020. PMID: 32930584
FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer.
Weiss A, Adler F, Buhles A, Stamm C, Fairhurst RA, Kiffe M, Sterker D, Centeleghe M, Wartmann M, Kinyamu-Akunda J, Schadt HS, Couttet P, Wolf A, Wang Y, Barzaghi-Rinaudo P, Murakami M, Kauffmann A, Knoepfel T, Buschmann N, Leblanc C, Mah R, Furet P, Blank J, Hofmann F, Sellers WR, Graus Porta D. Weiss A, et al. Among authors: couttet p. Mol Cancer Ther. 2019 Dec;18(12):2194-2206. doi: 10.1158/1535-7163.MCT-18-1291. Epub 2019 Aug 13. Mol Cancer Ther. 2019. PMID: 31409633
Imaging Mass Cytometry and Single-Cell Genomics Reveal Differential Depletion and Repletion of B-Cell Populations Following Ofatumumab Treatment in Cynomolgus Monkeys.
Theil D, Smith P, Huck C, Gilbart Y, Kakarieka A, Leppert D, Rauld C, Schmid C, Baumgartner R, Stuber N, Cordoba F, Dubost V, Darribat K, Jivkov M, Frieauff W, Kneuer R, Stoeckli M, Reinker S, Mansfield K, Carballido JM, Couttet P, Weckbecker G. Theil D, et al. Among authors: couttet p. Front Immunol. 2019 Jun 20;10:1340. doi: 10.3389/fimmu.2019.01340. eCollection 2019. Front Immunol. 2019. PMID: 31281311 Free PMC article.
Transcriptomic Analysis of Cholestatic Compounds In Vitro.
Parmentier C, Couttet P, Uteng M, Wolf A, Richert L. Parmentier C, et al. Among authors: couttet p. Methods Mol Biol. 2019;1981:175-186. doi: 10.1007/978-1-4939-9420-5_12. Methods Mol Biol. 2019. PMID: 31016655
34 results