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Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes.
Le Guen Y, Luo G, Ambati A, Damotte V, Jansen I, Yu E, Nicolas A, de Rojas I, Peixoto Leal T, Miyashita A, Bellenguez C, Lian MM, Parveen K, Morizono T, Park H, Grenier-Boley B, Naito T, Küçükali F, Talyansky SD, Yogeshwar SM, Sempere V, Satake W, Alvarez V, Arosio B, Belloy ME, Benussi L, Boland A, Borroni B, Bullido MJ, Caffarra P, Clarimon J, Daniele A, Darling D, Debette S, Deleuze JF, Dichgans M, Dufouil C, During E, Düzel E, Galimberti D, Garcia-Ribas G, García-Alberca JM, García-González P, Giedraitis V, Goldhardt O, Graff C, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Holstege H, Hort J, Jung YJ, Jürgen D, Kern S, Kuulasmaa T, Lee KH, Lin L, Masullo C, Mecocci P, Mehrabian S, de Mendonça A, Boada M, Mir P, Moebus S, Moreno F, Nacmias B, Nicolas G, Niida S, Nordestgaard BG, Papenberg G, Papma J, Parnetti L, Pasquier F, Pastor P, Peters O, Pijnenburg YAL, Piñol-Ripoll G, Popp J, Porcel LM, Puerta R, Pérez-Tur J, Rainero I, Ramakers I, Real LM, Riedel-Heller S, Rodriguez-Rodriguez E, Ross OA, Royo LJ, Rujescu D, Scarmeas N, Scheltens P, Scherbaum N, Schneider A, Seripa D, Skoog I, Solfrizzi V, Spalletta G, Squassina A, van Swieten J, Sánchez-Valle R, Tan EK, Tegos T… See abstract for full author list ➔ Le Guen Y, et al. Proc Natl Acad Sci U S A. 2023 Sep 5;120(36):e2302720120. doi: 10.1073/pnas.2302720120. Epub 2023 Aug 29. Proc Natl Acad Sci U S A. 2023. PMID: 37643212 Free PMC article.
Association of genetic variants of ABCA1 with Alzheimer's disease risk.
Rodríguez-Rodríguez E, Mateo I, Llorca J, Sánchez-Quintana C, Infante J, García-Gorostiaga I, Sánchez-Juan P, Berciano J, Combarros O. Rodríguez-Rodríguez E, et al. Am J Med Genet B Neuropsychiatr Genet. 2007 Oct 5;144B(7):964-8. doi: 10.1002/ajmg.b.30552. Am J Med Genet B Neuropsychiatr Genet. 2007. PMID: 17510946
Age-dependent association of KIBRA genetic variation and Alzheimer's disease risk.
Rodríguez-Rodríguez E, Infante J, Llorca J, Mateo I, Sánchez-Quintana C, García-Gorostiaga I, Sánchez-Juan P, Berciano J, Combarros O. Rodríguez-Rodríguez E, et al. Neurobiol Aging. 2009 Feb;30(2):322-4. doi: 10.1016/j.neurobiolaging.2007.07.003. Epub 2007 Aug 17. Neurobiol Aging. 2009. PMID: 17707552
Interaction between CD14 and LXRbeta genes modulates Alzheimer's disease risk.
Rodríguez-Rodríguez E, Sánchez-Juan P, Mateo I, Infante J, Sánchez-Quintana C, García-Gorostiaga I, Berciano J, Combarros O. Rodríguez-Rodríguez E, et al. J Neurol Sci. 2008 Jan 15;264(1-2):97-9. doi: 10.1016/j.jns.2007.08.001. Epub 2007 Sep 27. J Neurol Sci. 2008. PMID: 17900622
14-3-3 zeta and tau genes interactively decrease Alzheimer's disease risk.
Mateo I, Sánchez-Juan P, Rodríguez-Rodríguez E, Infante J, Fernández-Viadero C, Peña N, Berciano J, Combarros O. Mateo I, et al. Dement Geriatr Cogn Disord. 2008;25(4):317-20. doi: 10.1159/000119123. Epub 2008 Mar 4. Dement Geriatr Cogn Disord. 2008. PMID: 18319590
304 results