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141 results

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Page 1
EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption.
Pinilla M, Mazars R, Vergé R, Gorse L, Paradis M, Suire B, Santoni K, Robinson KS, Toh GA, Prouvensier L, Leon-Icaza SA, Hessel A, Péricat D, Murris M, Guet-Revillet H, Henras A, Buyck J, Ravet E, Zhong FL, Cougoule C, Planès R, Meunier E. Pinilla M, et al. J Exp Med. 2023 Oct 2;220(10):e20230104. doi: 10.1084/jem.20230104. Epub 2023 Aug 29. J Exp Med. 2023. PMID: 37642996 Free PMC article.
Irgm2 and Gate-16 cooperatively dampen Gram-negative bacteria-induced caspase-11 response.
Eren E, Planès R, Bagayoko S, Bordignon PJ, Chaoui K, Hessel A, Santoni K, Pinilla M, Lagrange B, Burlet-Schiltz O, Howard JC, Henry T, Yamamoto M, Meunier E. Eren E, et al. Among authors: pinilla m. EMBO Rep. 2020 Nov 5;21(11):e50829. doi: 10.15252/embr.202050829. Epub 2020 Oct 30. EMBO Rep. 2020. PMID: 33124769 Free PMC article.
Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology.
Bagayoko S, Leon-Icaza SA, Pinilla M, Hessel A, Santoni K, Péricat D, Bordignon PJ, Moreau F, Eren E, Boyancé A, Naser E, Lefèvre L, Berrone C, Iakobachvili N, Metais A, Rombouts Y, Lugo-Villarino G, Coste A, Attrée I, Frank DW, Clevers H, Peters PJ, Cougoule C, Planès R, Meunier E. Bagayoko S, et al. Among authors: pinilla m. PLoS Pathog. 2021 Sep 13;17(9):e1009927. doi: 10.1371/journal.ppat.1009927. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34516571 Free PMC article.
Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells.
Planès R, Pinilla M, Santoni K, Hessel A, Passemar C, Lay K, Paillette P, Valadão AC, Robinson KS, Bastard P, Lam N, Fadrique R, Rossi I, Pericat D, Bagayoko S, Leon-Icaza SA, Rombouts Y, Perouzel E, Tiraby M; COVID Human Genetic Effort; Zhang Q, Cicuta P, Jouanguy E, Neyrolles O, Bryant CE, Floto AR, Goujon C, Lei FZ, Martin-Blondel G, Silva S, Casanova JL, Cougoule C, Reversade B, Marcoux J, Ravet E, Meunier E. Planès R, et al. Among authors: pinilla m. Mol Cell. 2022 Jul 7;82(13):2385-2400.e9. doi: 10.1016/j.molcel.2022.04.033. Epub 2022 May 16. Mol Cell. 2022. PMID: 35594856 Free PMC article.
Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa.
Santoni K, Pericat D, Gorse L, Buyck J, Pinilla M, Prouvensier L, Bagayoko S, Hessel A, Leon-Icaza SA, Bellard E, Mazères S, Doz-Deblauwe E, Winter N, Paget C, Girard JP, Pham CTN, Cougoule C, Poincloux R, Lamkanfi M, Lefrançais E, Meunier E, Planès R. Santoni K, et al. Among authors: pinilla m. PLoS Pathog. 2022 Jul 18;18(7):e1010305. doi: 10.1371/journal.ppat.1010305. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35849616 Free PMC article.
Mechanistic basis for potassium efflux-driven activation of the human NLRP1 inflammasome.
Rozario P, Pinilla M, Gorse L, Vind AC, Robinson KS, Toh GA, Firdaus MJ, Martínez JF, Kerk SK, Lin Z, Chambers JC, Bekker-Jensen S, Meunier E, Zhong F. Rozario P, et al. Among authors: pinilla m. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2309579121. doi: 10.1073/pnas.2309579121. Epub 2024 Jan 4. Proc Natl Acad Sci U S A. 2024. PMID: 38175865 Free PMC article.
Computed tomographic features of Morel-Lavallée lesions in 3 cats.
Dziedzic-Nyrka N, Dancer S, Kaipak EF, Nowak L, Pinilla M, Carrera I, Garcia-Pertierra S, Clements DN, Schwarz T. Dziedzic-Nyrka N, et al. Among authors: pinilla m. J Am Vet Med Assoc. 2024 Oct 3:1-6. doi: 10.2460/javma.24.06.0429. Online ahead of print. J Am Vet Med Assoc. 2024. PMID: 39362272
Lipid and glucose profiles in pregnant women with HIV on tenofovir-based antiretroviral therapy.
Eke AC, Brummel SS, Aliyu MH, Stranix-Chibanda L, Eleje GU, Ezebialu IU, Korutaro V, Wabwire D, Matubu A, Mbengeranwa T, Chakhtoura N, Chinula L, McCarthy K, Knowles K, Krotje C, Linton MF, Dooley KE, Sax PE, Brown T, Lockman S; IMPAACT 2010/VESTED Study Team. Eke AC, et al. Clin Infect Dis. 2024 Sep 2:ciae441. doi: 10.1093/cid/ciae441. Online ahead of print. Clin Infect Dis. 2024. PMID: 39219495
Effects of preterm birth, maternal ART and breastfeeding on 24-month infant HIV-free survival in a randomized trial.
Dadabhai S, Chou VB, Pinilla M, Chinula L, Owor M, Violari A, Moodley D, Stranix-Chibanda L, Matubu TA, Chareka GT, Theron G, Kinikar AA, Mubiana-Mbewe M, Fairlie L, Bobat R, Mmbaga BT, Flynn PM, Taha TE, McCarthy KS, Browning R, Mofenson LM, Brummel SS, Fowler MG; IMPAACT PROMISE 1077BF/FF team. Dadabhai S, et al. Among authors: pinilla m. AIDS. 2024 Jul 15;38(9):1304-1313. doi: 10.1097/QAD.0000000000003878. Epub 2024 Mar 1. AIDS. 2024. PMID: 38427596 Free PMC article. Clinical Trial.
Weight Changes and Adverse Pregnancy Outcomes With Dolutegravir- and Tenofovir Alafenamide Fumarate-Containing Antiretroviral Treatment Regimens During Pregnancy and Postpartum.
Hoffman RM, Brummel S, Ziemba L, Chinula L, McCarthy K, Fairlie L, Jean-Philippe P, Chakhtoura N, Johnston B, Krotje C, Nematadzira TG, Nakayiwa F, Ndyanabangi V, Hanley S, Theron G, Violari A, João E, Correa MD  Jr, Hofer CB, Navanukroh O, Aurpibul L, Nevrekar N, Zash R, Shapiro R, Stringer JSA, Currier JS, Sax P, Lockman S; IMPAACT 2010/VESTED Study Team. Hoffman RM, et al. Clin Infect Dis. 2024 Jun 14;78(6):1617-1628. doi: 10.1093/cid/ciae001. Clin Infect Dis. 2024. PMID: 38180851 Clinical Trial.
141 results