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Augmentation Therapy for Severe Alpha-1 Antitrypsin Deficiency Improves Survival and Is Decoupled from Spirometric Decline-A Multinational Registry Analysis.
Fraughen DD, Ghosh AJ, Hobbs BD, Funk GC, Meischl T, Clarenbach CF, Sievi NA, Schmid-Scherzer K, McElvaney OJ, Murphy MP, Roche AD, Clarke L, Strand M, Vafai-Tabrizi F, Kelly G, Gunaratnam C, Carroll TP, McElvaney NG. Fraughen DD, et al. Among authors: ghosh aj. Am J Respir Crit Care Med. 2023 Nov 1;208(9):964-974. doi: 10.1164/rccm.202305-0863OC. Am J Respir Crit Care Med. 2023. PMID: 37624745 Free PMC article.
Comorbidity-Based Clusters Contain Chaos in COPD.
Ghosh AJ, Hobbs BD. Ghosh AJ, et al. Chest. 2020 Jul;158(1):11-12. doi: 10.1016/j.chest.2020.03.016. Epub 2020 Jul 2. Chest. 2020. PMID: 32654700 No abstract available.
Alpha-1 Antitrypsin MZ Heterozygosity Is an Endotype of Chronic Obstructive Pulmonary Disease.
Ghosh AJ, Hobbs BD, Moll M, Saferali A, Boueiz A, Yun JH, Sciurba F, Barwick L, Limper AH, Flaherty K, Criner G, Brown KK, Wise R, Martinez FJ, Lomas D, Castaldi PJ, Carey VJ, DeMeo DL, Cho MH, Silverman EK, Hersh CP; COPDGene Investigators. Ghosh AJ, et al. Am J Respir Crit Care Med. 2022 Feb 1;205(3):313-323. doi: 10.1164/rccm.202106-1404OC. Am J Respir Crit Care Med. 2022. PMID: 34762809 Free PMC article.
Alternative poly-adenylation modulates α1-antitrypsin expression in chronic obstructive pulmonary disease.
Lackey L, Coria A, Ghosh AJ, Grayeski P, Hatfield A, Shankar V, Platig J, Xu Z, Ramos SBV, Silverman EK, Ortega VE, Cho MH, Hersh CP, Hobbs BD, Castaldi P, Laederach A. Lackey L, et al. Among authors: ghosh aj. PLoS Genet. 2021 Nov 16;17(11):e1009912. doi: 10.1371/journal.pgen.1009912. eCollection 2021 Nov. PLoS Genet. 2021. PMID: 34784346 Free PMC article.
Blood gene expression risk profiles and interstitial lung abnormalities: COPDGene and ECLIPSE cohort studies.
Moll M, Hobbs BD, Menon A, Ghosh AJ, Putman RK, Hino T, Hata A, Silverman EK, Quackenbush J, Castaldi PJ, Hersh CP, McGeachie MJ, Sin DD, Tal-Singer R, Nishino M, Hatabu H, Hunninghake GM, Cho MH. Moll M, et al. Among authors: ghosh aj. Respir Res. 2022 Jun 17;23(1):157. doi: 10.1186/s12931-022-02077-8. Respir Res. 2022. PMID: 35715807 Free PMC article.
Prevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease.
Tran TV, Kinney GL, Comellas A, Hoth KF, Baldomero AK, Mamary AJ, Curtis JL, Hanania N, Casaburi R, Young KA, Kim V, Make B, Wan ES, Diaz AA, Hokanson J, Crapo JD, Silverman EK, Bhatt SP, Regan E, Fortis S; COPDGene® Investigators – Core Units; COPDGene® Investigators – Clinical Centers. Tran TV, et al. Respir Med. 2023 Mar;208:107126. doi: 10.1016/j.rmed.2023.107126. Epub 2023 Jan 28. Respir Med. 2023. PMID: 36717002 Free PMC article.
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