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Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells.
Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Chauss D, et al. Among authors: portilla d. Nat Immunol. 2022 Jan;23(1):62-74. doi: 10.1038/s41590-021-01080-3. Epub 2021 Nov 11. Nat Immunol. 2022. PMID: 34764490 Free PMC article.
Hematological Parameters, Lipid Profile, and Cardiovascular Risk Analysis Among Genotype-Controlled Indigenous Kiwcha Men and Women Living at Low and High Altitudes.
Ortiz-Prado E, Portilla D, Mosquera-Moscoso J, Simbaña-Rivera K, Duta D, Ochoa I, Burgos G, Izquierdo-Condoy JS, Vásconez E, Calvopiña M, Viscor G. Ortiz-Prado E, et al. Among authors: portilla d. Front Physiol. 2021 Oct 25;12:749006. doi: 10.3389/fphys.2021.749006. eCollection 2021. Front Physiol. 2021. PMID: 34759840 Free PMC article.
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.
Yan B, Freiwald T, Chauss D, Wang L, West E, Mirabelli C, Zhang CJ, Nichols EM, Malik N, Gregory R, Bantscheff M, Ghidelli-Disse S, Kolev M, Frum T, Spence JR, Sexton JZ, Alysandratos KD, Kotton DN, Pittaluga S, Bibby J, Niyonzima N, Olson MR, Kordasti S, Portilla D, Wobus CE, Laurence A, Lionakis MS, Kemper C, Afzali B, Kazemian M. Yan B, et al. Among authors: portilla d. Sci Immunol. 2021 Apr 7;6(58):eabg0833. doi: 10.1126/sciimmunol.abg0833. Sci Immunol. 2021. PMID: 33827897 Free PMC article.
An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19.
McGregor R, Chauss D, Freiwald T, Yan B, Wang L, Nova-Lamperti E, Zhang Z, Teague H, West EE, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz D, Portilla D, John S, Lavender P, Lionakis MS, Mehta NN, Kemper C, Cooper N, Lombardi G, Laurence A, Kazemian M, Afzali B. McGregor R, et al. Among authors: portilla d. bioRxiv [Preprint]. 2020 Jul 19:2020.07.18.210161. doi: 10.1101/2020.07.18.210161. bioRxiv. 2020. PMID: 32743590 Free PMC article. Preprint.
Protective role of DJ-1 in endotoxin-induced acute kidney injury.
Leeds J, Scindia Y, Loi V, Wlazlo E, Ghias E, Cechova S, Portilla D, Ledesma J, Swaminathan S. Leeds J, et al. Among authors: portilla d. Am J Physiol Renal Physiol. 2020 Oct 1;319(4):F654-F663. doi: 10.1152/ajprenal.00064.2020. Epub 2020 Jul 27. Am J Physiol Renal Physiol. 2020. PMID: 32715759 Free PMC article.
78 results