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Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis.
Munugalavadla V, Sims EC, Borneo J, Chan RJ, Kapur R. Munugalavadla V, et al. Among authors: kapur r. Blood. 2007 Sep 1;110(5):1612-20. doi: 10.1182/blood-2006-10-053058. Epub 2007 May 4. Blood. 2007. PMID: 17483298 Free PMC article.
Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins.
Li Y, Yan J, De P, Chang HC, Yamauchi A, Christopherson KW 2nd, Paranavitana NC, Peng X, Kim C, Munugalavadla V, Kapur R, Chen H, Shou W, Stone JC, Kaplan MH, Dinauer MC, Durden DL, Quilliam LA. Li Y, et al. Among authors: kapur r. J Immunol. 2007 Dec 15;179(12):8322-31. doi: 10.4049/jimmunol.179.12.8322. J Immunol. 2007. PMID: 18056377 Free PMC article.
647 results