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Evolutionary history of MEK1 illuminates the nature of deleterious mutations.
Andrianova EP, Marmion RA, Shvartsman SY, Zhulin IB. Andrianova EP, et al. Among authors: shvartsman sy. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2304184120. doi: 10.1073/pnas.2304184120. Epub 2023 Aug 14. Proc Natl Acad Sci U S A. 2023. PMID: 37579140 Free PMC article.
Dynamic Control of dNTP Synthesis in Early Embryos.
Song Y, Marmion RA, Park JO, Biswas D, Rabinowitz JD, Shvartsman SY. Song Y, et al. Among authors: shvartsman sy. Dev Cell. 2017 Aug 7;42(3):301-308.e3. doi: 10.1016/j.devcel.2017.06.013. Epub 2017 Jul 20. Dev Cell. 2017. PMID: 28735680 Free PMC article.
Functional divergence caused by mutations in an energetic hotspot in ERK2.
Taylor CA 4th, Cormier KW, Keenan SE, Earnest S, Stippec S, Wichaidit C, Juang YC, Wang J, Shvartsman SY, Goldsmith EJ, Cobb MH. Taylor CA 4th, et al. Among authors: shvartsman sy. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15514-15523. doi: 10.1073/pnas.1905015116. Epub 2019 Jul 11. Proc Natl Acad Sci U S A. 2019. PMID: 31296562 Free PMC article.
Optimizing photoswitchable MEK.
Patel AL, Yeung E, McGuire SE, Wu AY, Toettcher JE, Burdine RD, Shvartsman SY. Patel AL, et al. Among authors: shvartsman sy. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25756-25763. doi: 10.1073/pnas.1912320116. Epub 2019 Dec 3. Proc Natl Acad Sci U S A. 2019. PMID: 31796593 Free PMC article.
Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua.
Keenan SE, Blythe SA, Marmion RA, Djabrayan NJ, Wieschaus EF, Shvartsman SY. Keenan SE, et al. Among authors: shvartsman sy. Dev Cell. 2020 Mar 23;52(6):794-801.e4. doi: 10.1016/j.devcel.2020.02.004. Epub 2020 Mar 5. Dev Cell. 2020. PMID: 32142631 Free PMC article.
Molecular mechanisms underlying cellular effects of human MEK1 mutations.
Marmion RA, Yang L, Goyal Y, Jindal GA, Wetzel JL, Singh M, Schüpbach T, Shvartsman SY. Marmion RA, et al. Among authors: shvartsman sy. Mol Biol Cell. 2021 Apr 19;32(9):974-983. doi: 10.1091/mbc.E20-10-0625. Epub 2021 Jan 21. Mol Biol Cell. 2021. PMID: 33476180 Free PMC article.
Temporal integration of inductive cues on the way to gastrulation.
McFann S, Dutta S, Toettcher JE, Shvartsman SY. McFann S, et al. Among authors: shvartsman sy. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2102691118. doi: 10.1073/pnas.2102691118. Proc Natl Acad Sci U S A. 2021. PMID: 34083443 Free PMC article.
Clonal dominance in excitable cell networks.
Alsous JI, Rozman J, Marmion RA, Košmrlj A, Shvartsman SY. Alsous JI, et al. Among authors: shvartsman sy. Nat Phys. 2021 Dec;17(12):1391-1395. doi: 10.1038/s41567-021-01383-0. Epub 2021 Nov 1. Nat Phys. 2021. PMID: 35242199 Free PMC article.
Stochastic phenotypes in RAS-dependent developmental diseases.
Marmion RA, Simpkins AG, Barrett LA, Denberg DW, Zusman S, Schottenfeld-Roames J, Schüpbach T, Shvartsman SY. Marmion RA, et al. Among authors: shvartsman sy. Curr Biol. 2023 Mar 13;33(5):807-816.e4. doi: 10.1016/j.cub.2023.01.008. Epub 2023 Jan 26. Curr Biol. 2023. PMID: 36706752 Free PMC article.
172 results