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Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer.
Schmidt DR, Gramatikov IMT, Sheen A, Williams CL, Hurwitz M, Dodge LE, Holupka E, Kiger WS 3rd, Cornwall-Brady MR, Huang W, Mak HH, Cormier KS, Condon C, Dane Wittrup K, Yilmaz ÖH, Stevenson MA, Down JD, Floyd SR, Roper J, Vander Heiden MG. Schmidt DR, et al. Among authors: down jd. Commun Med (Lond). 2023 Aug 9;3(1):108. doi: 10.1038/s43856-023-00336-3. Commun Med (Lond). 2023. PMID: 37558833 Free PMC article.
Targeted hematopoietic stem cell depletion through SCF-blockade.
Chan YY, Ho PY, Dib C, Swartzrock L, Rayburn M, Willner H, Ko E, Ho K, Down JD, Wilkinson AC, Nakauchi H, Denis M, Cool T, Czechowicz A. Chan YY, et al. Among authors: down jd. Stem Cell Res Ther. 2024 Oct 29;15(1):387. doi: 10.1186/s13287-024-03981-0. Stem Cell Res Ther. 2024. PMID: 39473008 Free PMC article.
A C57L/J Mouse Model of the Delayed Effects of Acute Radiation Exposure in the Context of Evolving Multi-Organ Dysfunction and Failure after Total-Body Irradiation with 2.5% Bone Marrow Sparing.
Gibbs A, Gupta P, Mali B, Poirier Y, Gopalakrishnan M, Newman D, Zodda A, Down JD, Serebrenik AA, Kaytor MD, Jacksone IL. Gibbs A, et al. Among authors: down jd. Radiat Res. 2023 Apr 1;199(4):319-335. doi: 10.1667/RADE-22-00178.1. Radiat Res. 2023. PMID: 36857032 Free PMC article.
Ex Vivo Selection of Transduced Hematopoietic Stem Cells for Gene Therapy of β-Hemoglobinopathies.
Bhukhai K, de Dreuzy E, Giorgi M, Colomb C, Negre O, Denaro M, Gillet-Legrand B, Cheuzeville J, Paulard A, Trebeden-Negre H, Borwornpinyo S, Sii-Felice K, Maouche L, Down JD, Leboulch P, Payen E. Bhukhai K, et al. Among authors: down jd. Mol Ther. 2018 Feb 7;26(2):480-495. doi: 10.1016/j.ymthe.2017.10.015. Epub 2017 Oct 24. Mol Ther. 2018. PMID: 29221807 Free PMC article.
88 results