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Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk.
Li Y, Chaurasia B, Rahman MM, Kaddai V, Maschek JA, Berg JA, Wilkerson JL, Mahmassani ZS, Cox J, Wei P, Meikle PJ, Atkinson D, Wang L, Poss AM, Playdon MC, Tippetts TS, Mousa EM, Nittayaboon K, Anandh Babu PV, Drummond MJ, Clevers H, Shayman JA, Hirabayashi Y, Holland WL, Rutter J, Edgar BA, Summers SA. Li Y, et al. Among authors: shayman ja. Gastroenterology. 2023 Nov;165(5):1136-1150. doi: 10.1053/j.gastro.2023.07.017. Epub 2023 Aug 2. Gastroenterology. 2023. PMID: 37541526 Free PMC article.
Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15.
Jain R, Geoghegan G, Davidson J, Nesbitt DJ, Abe A, Chao X, James I, Cavanagh A, Michorowska S, Verma R, Scheuler K, Hinkovska-Galcheva V, Shishkova E, Ding WX, Coon JJ, Shayman JA, Simcox JA. Jain R, et al. Among authors: shayman ja. bioRxiv [Preprint]. 2023 Nov 10:2023.11.03.565498. doi: 10.1101/2023.11.03.565498. bioRxiv. 2023. PMID: 37986778 Free PMC article. Preprint.
Inhibitors of Glucosylceramide Synthase.
Shayman JA, Hinkovska-Galcheva V, Shu L. Shayman JA, et al. Methods Mol Biol. 2023;2613:271-288. doi: 10.1007/978-1-0716-2910-9_20. Methods Mol Biol. 2023. PMID: 36587085
Optimization of Eliglustat-Based Glucosylceramide Synthase Inhibitors as Substrate Reduction Therapy for Gaucher Disease Type 3.
Wilson MW, Shu L, Hinkovska-Galcheva V, Jin Y, Rajeswaran W, Abe A, Zhao T, Luo R, Wang L, Wen B, Liou B, Fannin V, Sun D, Sun Y, Shayman JA, Larsen SD. Wilson MW, et al. Among authors: shayman ja. ACS Chem Neurosci. 2020 Oct 21;11(20):3464-3473. doi: 10.1021/acschemneuro.0c00558. Epub 2020 Oct 9. ACS Chem Neurosci. 2020. PMID: 33035424 Free PMC article.
160 results