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Page 1
Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis.
Liu W, Yalcinkaya M, Maestre IF, Olszewska M, Ampomah PB, Heimlich JB, Wang R, Vela PS, Xiao T, Bick AG, Levine R, Papapetrou EP, Libby P, Tabas I, Wang N, Tall AR. Liu W, et al. Among authors: heimlich jb. Nat Cardiovasc Res. 2023 Jun;2(6):572-586. doi: 10.1038/s44161-023-00281-3. Epub 2023 Jun 8. Nat Cardiovasc Res. 2023. PMID: 37539077 Free PMC article.
Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.
Yu Z, Fidler TP, Ruan Y, Vlasschaert C, Nakao T, Uddin MM, Mack T, Niroula A, Heimlich JB, Zekavat SM, Gibson CJ, Griffin GK, Wang Y, Peloso GM, Heard-Costa N, Levy D, Vasan RS, Aguet F, Ardlie KG, Taylor KD, Rich SS, Rotter JI, Libby P, Jaiswal S, Ebert BL, Bick AG, Tall AR, Natarajan P. Yu Z, et al. Among authors: heimlich jb. J Clin Invest. 2023 Sep 15;133(18):e168597. doi: 10.1172/JCI168597. J Clin Invest. 2023. PMID: 37498674 Free PMC article.
Cost-Effective and Scalable Clonal Hematopoiesis Assay Provides Insight into Clonal Dynamics.
Mack T, Vlasschaert C, von Beck K, Silver AJ, Heimlich JB, Poisner H, Condon HR, Ulloa J, Sochacki AL, Spaulding TP, Kishtagari A, Bejan CA, Xu Y, Savona MR, Jones A, Bick AG. Mack T, et al. Among authors: heimlich jb. J Mol Diagn. 2024 Jul;26(7):563-573. doi: 10.1016/j.jmoldx.2024.03.007. Epub 2024 Apr 6. J Mol Diagn. 2024. PMID: 38588769 Free article.
Germline genetics, disease, and exposure to medication influence longitudinal dynamics of clonal hematopoiesis.
Mack T, Pershad Y, Vlasschaert C, Bejan CA, Heimlich JB, Li Y, Mickels NA, Van Amburg JC, Ulloa J, Silver AJ, Luo LY, Jones A, Ferrell PB, Kishtagari A, Xu Y, Savona MR, Bick AG. Mack T, et al. Among authors: heimlich jb. Haematologica. 2024 Nov 14. doi: 10.3324/haematol.2024.286513. Online ahead of print. Haematologica. 2024. PMID: 39540221 Free article.
A blueprint for pursuing therapeutic interventions and early phase clinical trials in clonal haematopoiesis.
Haque T, Shastri A, Desai P, Xie Z, Hammond D, King Z, Kishtagari A, Madanat YF, Abaza Y, Silver AJ, Singh A, Borate UM, Heimlich JB, Slosky DA, Bolton KL, Patnaik MS, Bick AG, Verma AK, Jaiswal S, Steensma DP, Savona MR. Haque T, et al. Among authors: heimlich jb. Br J Haematol. 2024 Dec 9. doi: 10.1111/bjh.19925. Online ahead of print. Br J Haematol. 2024. PMID: 39653653 Review.
Clonal hematopoiesis and inflammation in the vasculature: CHIVE, a prospective, longitudinal clonal hematopoiesis cohort and biorepository.
Shannon ML, Heimlich JB, Olson S, Debevec A, Copeland Z, Kishtagari A, Vlasschaert C, Snider C, Silver AJ, Brown D, Spaulding T, Bhatta M, Pugh K, Stockton SS, Ulloa J, Xu Y, Baljevic M, Moslehi J, Jahangir E, Ferrell PB, Slosky D, Bick AG, Savona MR. Shannon ML, et al. Among authors: heimlich jb. Blood Adv. 2024 Jul 9;8(13):3453-3463. doi: 10.1182/bloodadvances.2023011510. Blood Adv. 2024. PMID: 38608257 Free PMC article.
Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation.
Heimlich JB, Bhat P, Parker AC, Jenkins MT, Vlasschaert C, Ulloa J, Van Amburg JC, Potts CR, Olson S, Silver AJ, Ahmad A, Sharber B, Brown D, Hu N, van Galen P, Savona MR, Bick AG, Ferrell PB. Heimlich JB, et al. Blood Adv. 2024 Jul 23;8(14):3665-3678. doi: 10.1182/bloodadvances.2023011445. Blood Adv. 2024. PMID: 38507736 Free PMC article.
24 results