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Page 1
Genetic insights into resting heart rate and its role in cardiovascular disease.
van de Vegte YJ, Eppinga RN, van der Ende MY, Hagemeijer YP, Mahendran Y, Salfati E, Smith AV, Tan VY, Arking DE, Ntalla I, Appel EV, Schurmann C, Brody JA, Rueedi R, Polasek O, Sveinbjornsson G, Lecoeur C, Ladenvall C, Zhao JH, Isaacs A, Wang L, Luan J, Hwang SJ, Mononen N, Auro K, Jackson AU, Bielak LF, Zeng L, Shah N, Nethander M, Campbell A, Rankinen T, Pechlivanis S, Qi L, Zhao W, Rizzi F, Tanaka T, Robino A, Cocca M, Lange L, Müller-Nurasyid M, Roselli C, Zhang W, Kleber ME, Guo X, Lin HJ, Pavani F, Galesloot TE, Noordam R, Milaneschi Y, Schraut KE, den Hoed M, Degenhardt F, Trompet S, van den Berg ME, Pistis G, Tham YC, Weiss S, Sim XS, Li HL, van der Most PJ, Nolte IM, Lyytikäinen LP, Said MA, Witte DR, Iribarren C, Launer L, Ring SM, de Vries PS, Sever P, Linneberg A, Bottinger EP, Padmanabhan S, Psaty BM, Sotoodehnia N, Kolcic I; DCCT/EDIC Research Group; Arnar DO, Gudbjartsson DF, Holm H, Balkau B, Silva CT, Newton-Cheh CH, Nikus K, Salo P, Mohlke KL, Peyser PA, Schunkert H, Lorentzon M, Lahti J, Rao DC, Cornelis MC, Faul JD, Smith JA, Stolarz-Skrzypek K, Bandinelli S, Concas MP, Sinagra G, Meitinger T, Waldenberger M, Sinner MF, Strauch K, Delgado GE, Taylor KD,… See abstract for full author list ➔ van de Vegte YJ, et al. Among authors: mahendran y. Nat Commun. 2023 Aug 2;14(1):4646. doi: 10.1038/s41467-023-39521-2. Nat Commun. 2023. PMID: 37532724 Free PMC article.
Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis.
Skaaby T, Kilpeläinen TO, Taylor AE, Mahendran Y, Wong A, Ahluwalia TS, Paternoster L, Trompet S, Stott DJ, Flexeder C, Zhou A, Brusselle G, Sajjad A, Lahousse L, Tiemeier H, Have CT, Thuesen BH, Kårhus LL, Møllehave LT, Leth-Møller KB, Shabanzadeh DM, Gonzalez-Quintela A, Power C, Hyppönen E, Kuh D, Hardy R, Meitinger T, Jukema JW, Völker U, Nauck M, Völzke H, Friedrich N, Bonten TN, Noordam R, Mook-Kanamori DO, Tolstrup JS, Taube C, Peters A, Grallert H, Strauch K, Schulz H, Grarup N, Hansen T, Pedersen O, Burgess S, Munafò MR, Linneberg A. Skaaby T, et al. Among authors: mahendran y. Addiction. 2019 Feb;114(2):216-225. doi: 10.1111/add.14438. Epub 2018 Oct 30. Addiction. 2019. PMID: 30209858 Free PMC article.
Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis.
Skaaby T, Kilpeläinen TO, Mahendran Y, Huang LO, Sallis H, Thuesen BH, Kårhus LL, Leth-Møller KB, Grarup N, Hansen T, Pedersen O, Burgess S, Munafò MR, Linneberg A. Skaaby T, et al. Among authors: mahendran y. Eur J Epidemiol. 2022 Jul;37(7):713-722. doi: 10.1007/s10654-021-00826-5. Epub 2022 Jan 3. Eur J Epidemiol. 2022. PMID: 34978666 Free PMC article.
An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese.
Graae AS, Hollensted M, Kloppenborg JT, Mahendran Y, Schnurr TM, Appel EVR, Rask J, Nielsen TRH, Johansen MØ, Linneberg A, Jørgensen ME, Grarup N, Kadarmideen HN, Holst B, Pedersen O, Holm JC, Hansen T. Graae AS, et al. Among authors: mahendran y. Diabetologia. 2018 Aug;61(8):1769-1779. doi: 10.1007/s00125-018-4640-0. Epub 2018 May 31. Diabetologia. 2018. PMID: 29855666 Free PMC article.
Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology.
Schnurr TM, Gjesing AP, Sandholt CH, Jonsson A, Mahendran Y, Have CT, Ekstrøm CT, Bjerregaard AL, Brage S, Witte DR, Jørgensen ME, Aadahl M, Thuesen BH, Linneberg A, Eiberg H, Pedersen O, Grarup N, Kilpeläinen TO, Hansen T. Schnurr TM, et al. Among authors: mahendran y. PLoS One. 2016 Nov 15;11(11):e0166738. doi: 10.1371/journal.pone.0166738. eCollection 2016. PLoS One. 2016. PMID: 27846319 Free PMC article.
Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.
Tabassum R, Chauhan G, Dwivedi OP, Mahajan A, Jaiswal A, Kaur I, Bandesh K, Singh T, Mathai BJ, Pandey Y, Chidambaram M, Sharma A, Chavali S, Sengupta S, Ramakrishnan L, Venkatesh P, Aggarwal SK, Ghosh S, Prabhakaran D, Srinath RK, Saxena M, Banerjee M, Mathur S, Bhansali A, Shah VN, Madhu SV, Marwaha RK, Basu A, Scaria V, McCarthy MI; DIAGRAM; INDICO; Venkatesan R, Mohan V, Tandon N, Bharadwaj D. Tabassum R, et al. Diabetes. 2013 Mar;62(3):977-86. doi: 10.2337/db12-0406. Epub 2012 Dec 3. Diabetes. 2013. PMID: 23209189 Free PMC article.
Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses.
Engelbrechtsen L, Mahendran Y, Jonsson A, Gjesing AP, Weeke PE, Jørgensen ME, Færch K, Witte DR, Holst JJ, Jørgensen T, Grarup N, Pedersen O, Vestergaard H, Torekov S, Kanters JK, Hansen T. Engelbrechtsen L, et al. Among authors: mahendran y. BMC Genet. 2018 Mar 16;19(1):15. doi: 10.1186/s12863-018-0602-2. BMC Genet. 2018. PMID: 29548277 Free PMC article.
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes.
Grarup N, Moltke I, Andersen MK, Dalby M, Vitting-Seerup K, Kern T, Mahendran Y, Jørsboe E, Larsen CVL, Dahl-Petersen IK, Gilly A, Suveges D, Dedoussis G, Zeggini E, Pedersen O, Andersson R, Bjerregaard P, Jørgensen ME, Albrechtsen A, Hansen T. Grarup N, et al. Among authors: mahendran y. Nat Genet. 2018 Feb;50(2):172-174. doi: 10.1038/s41588-017-0022-7. Epub 2018 Jan 8. Nat Genet. 2018. PMID: 29311636 Free PMC article.
24 results