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A nitroalkene derivative of salicylate alleviates diet-induced obesity by activating creatine metabolism and non-shivering thermogenesis.
Cal K, Leyva A, Rodríguez-Duarte J, Ruiz S, Santos L, Colella L, Ingold M, Vilaseca C, Galliussi G, Ziegler L, Peclat TR, Bresque M, Handy RM, King R, Dos Reis LM, Espasandin C, Breining P, Dapueto R, Lopez A, Thompson KL, Agorrody G, DeVallance E, Meadows E, Lewis SE, Barbosa GCS, de Souza LOL, Chichierchio MS, Valez V, Aicardo A, Contreras P, Vendelbo MH, Jakobsen S, Kamaid A, Porcal W, Calliari A, Verdes JM, Du J, Wang Y, Hollander JM, White TA, Radi R, Moyna G, Quijano C, O'Doherty R, Moraes-Vieira P, Holloway GP, Leonardi R, Mori MA, Camacho-Pereira J, Kelley EE, Duran R, Lopez GV, Batthyány C, Chini EN, Escande C. Cal K, et al. Among authors: leyva a. Res Sq [Preprint]. 2023 Jul 12:rs.3.rs-3101395. doi: 10.21203/rs.3.rs-3101395/v1. Res Sq. 2023. PMID: 37502859 Free PMC article. Preprint.
DiagnoProt: a tool for discovery of new molecules by mass spectrometry.
Silva ARF, Lima DB, Leyva A, Duran R, Batthyany C, Aquino PF, Leal JC, Rodriguez JE, Domont GB, Santos MDM, Chamot-Rooke J, Barbosa VC, Carvalho PC. Silva ARF, et al. Among authors: leyva a. Bioinformatics. 2017 Jun 15;33(12):1883-1885. doi: 10.1093/bioinformatics/btx093. Bioinformatics. 2017. PMID: 28186229
A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo.
Santos L, Colman L, Contreras P, Chini CC, Carlomagno A, Leyva A, Bresque M, Marmisolle I, Quijano C, Durán R, Irigoín F, Prieto-Echagüe V, Vendelbo MH, Sotelo-Silveira JR, Chini EN, Badano JL, Calliari AJ, Escande C. Santos L, et al. Among authors: leyva a. Sci Rep. 2019 Oct 7;9(1):14381. doi: 10.1038/s41598-019-50789-7. Sci Rep. 2019. PMID: 31591441 Free PMC article.
Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: Molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response.
Lima A, Leyva A, Rivera B, Portela MM, Gil M, Cascioferro A, Lisa MN, Wehenkel A, Bellinzoni M, Carvalho PC, Batthyány C, Alvarez MN, Brosch R, Alzari PM, Durán R. Lima A, et al. Among authors: leyva a. J Proteomics. 2021 Jul 30;244:104276. doi: 10.1016/j.jprot.2021.104276. Epub 2021 May 24. J Proteomics. 2021. PMID: 34044169
Decreased proteasomal cleavage at nitrotyrosine sites in proteins and peptides.
Ott C, Tomasina F, Campolo N, Bartesaghi S, Mastrogiovanni M, Leyva A, Batthyány C, Meinl W, Grune T, Radi R. Ott C, et al. Among authors: leyva a. Redox Biol. 2021 Oct;46:102106. doi: 10.1016/j.redox.2021.102106. Epub 2021 Aug 18. Redox Biol. 2021. PMID: 34455147 Free PMC article.
4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification.
Kiyuna LA, Candido DS, Bechara LRG, Jesus ICG, Ramalho LS, Krum B, Albuquerque RP, Campos JC, Bozi LHM, Zambelli VO, Alves AN, Campolo N, Mastrogiovanni M, Bartesaghi S, Leyva A, Durán R, Radi R, Arantes GM, Cunha-Neto E, Mori MA, Chen CH, Yang W, Mochly-Rosen D, MacRae IJ, Ferreira LRP, Ferreira JCB. Kiyuna LA, et al. Among authors: leyva a. Eur Heart J. 2023 Nov 21;44(44):4696-4712. doi: 10.1093/eurheartj/ehad662. Eur Heart J. 2023. PMID: 37944136
227 results