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LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function.
Kumaraswamy A, Duan Z, Flores D, Zhang C, Sehrawat A, Hu YM, Swaim OA, Rodansky E, Storck WK, Kuleape JA, Bedi K, Mannan R, Wang XM, Udager A, Ravikumar V, Bankhead A 3rd, Coleman I, Lee JK, Morrissey C, Nelson PS, Chinnaiyan AM, Rao A, Xia Z, Yates JA, Alumkal JJ. Kumaraswamy A, et al. Among authors: mannan r. JCI Insight. 2023 Aug 8;8(15):e167440. doi: 10.1172/jci.insight.167440. JCI Insight. 2023. PMID: 37440313 Free PMC article.
Deciphering intratumor heterogeneity in clear cell renal cell carcinoma utilizing clinicopathologic and molecular platforms.
Vormittag-Nocito E, Mannan R, Wang X, Chinnaiyan A, Zhang Y, Zelenka-Wang S, Cao X, Morgan TM, Hafez K, Vaishampayan U, Abdulfatah E, Chinnaiyan AM, Dhanasekaran SM, Mehra R. Vormittag-Nocito E, et al. Among authors: mannan r. Hum Pathol. 2022 Dec;130:95-109. doi: 10.1016/j.humpath.2022.10.009. Epub 2022 Oct 27. Hum Pathol. 2022. PMID: 36511267
Lessons from 801 clinical TFE3/TFEB fluorescence in situ hybridization assays performed on renal cell carcinoma suspicious for MiTF family aberrations.
Wang XM, Shao L, Xiao H, Myers JL, Pantanowitz L, Skala SL, Udager AM, Vaishampayan U, Mannan R, Dhanasekaran SM, Chinnaiyan AM, Betz BL, Brown N, Mehra R. Wang XM, et al. Among authors: mannan r. Am J Clin Pathol. 2023 Dec 1;160(6):549-554. doi: 10.1093/ajcp/aqad089. Am J Clin Pathol. 2023. PMID: 37499055 Review.
Clinically relevant humanized mouse models of metastatic prostate cancer to evaluate cancer therapies.
Kostlan RJ, Phoenix JT, Budreika A, Ferrari MG, Khurana N, Cho JE, Juckette K, McCollum BL, Moskal R, Mannan R, Qiao Y, Griend DJV, Chinnaiyan AM, Kregel S. Kostlan RJ, et al. Among authors: mannan r. bioRxiv [Preprint]. 2023 Oct 17:2023.10.13.562280. doi: 10.1101/2023.10.13.562280. bioRxiv. 2023. Update in: Mol Cancer Res. 2024 Sep 4;22(9):826-839. doi: 10.1158/1541-7786.MCR-23-0904 PMID: 37904960 Free PMC article. Updated. Preprint.
Hybrid Oncocytic Tumors (HOTs) in Birt-Hogg-Dubé Syndrome Patients-A Tale of Two Cities: Sequencing Analysis Reveals Dual Lineage Markers Capturing the 2 Cellular Populations of HOT.
Wang XM, Mannan R, Zhang Y, Chinnaiyan A, Rangaswamy R, Chugh S, Su F, Cao X, Wang R, Skala SL, Hafez KS, Vaishampayan U, Mckenney J, Picken MM, Gupta S, Alaghehbandan R, Tretiakova M, Argani P, Chinnaiyan AM, Dhanasekaran SM, Mehra R. Wang XM, et al. Among authors: mannan r. Am J Surg Pathol. 2024 Feb 1;48(2):163-173. doi: 10.1097/PAS.0000000000002152. Epub 2023 Nov 24. Am J Surg Pathol. 2024. PMID: 37994665 Free PMC article.
Expression of L1 Cell Adhesion Molecule, a Nephronal Principal Cell Marker, in Nephrogenic Adenoma.
Mannan R, Wang X, Mahapatra S, Wang S, Chinnaiyan AK, Skala SL, Zhang Y, McMurry LM, Zelenka-Wang S, Cao X, Sangoi AR, Dadhania V, Picken MM, Menon S, Al-Ahmadie H, Chinnaiyan AM, Dhanasekaran SM, Mehra R. Mannan R, et al. Mod Pathol. 2024 Aug;37(8):100540. doi: 10.1016/j.modpat.2024.100540. Epub 2024 Jun 18. Mod Pathol. 2024. PMID: 38901674 Free article.
Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition.
Chang Y, Wang X, Yang J, Tien JC, Mannan R, Cruz G, Zhang Y, Vo JN, Magnuson B, Mahapatra S, Cho H, Dhanasekaran SM, Wang C, Wang Z, Zhou L, Zhou K, Zhou Y, Zhang P, Huang W, Xiao L, Liu WR, Hamadeh R, Su F, Wang R, Miner SJ, Cao X, Cheng Y, Mehra R, Ding K, Chinnaiyan AM. Chang Y, et al. Among authors: mannan r. Cell Rep Med. 2024 Oct 15;5(10):101752. doi: 10.1016/j.xcrm.2024.101752. Epub 2024 Sep 30. Cell Rep Med. 2024. PMID: 39353441 Free PMC article.
167 results