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LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function.
Kumaraswamy A, Duan Z, Flores D, Zhang C, Sehrawat A, Hu YM, Swaim OA, Rodansky E, Storck WK, Kuleape JA, Bedi K, Mannan R, Wang XM, Udager A, Ravikumar V, Bankhead A 3rd, Coleman I, Lee JK, Morrissey C, Nelson PS, Chinnaiyan AM, Rao A, Xia Z, Yates JA, Alumkal JJ. Kumaraswamy A, et al. Among authors: bedi k. JCI Insight. 2023 Aug 8;8(15):e167440. doi: 10.1172/jci.insight.167440. JCI Insight. 2023. PMID: 37440313 Free PMC article.
KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Noncanonical Activin Pathway.
Yi Z, Wei S, Jin L, Jeyarajan S, Yang J, Gu Y, Kim HS, Schechter S, Lu S, Paulsen MT, Bedi K, Narayanan IV, Ljungman M, Crawford HC, Pasca di Magliano M, Ge K, Dou Y, Shi J. Yi Z, et al. Among authors: bedi k. Cell Mol Gastroenterol Hepatol. 2022;13(2):643-667. doi: 10.1016/j.jcmgh.2021.09.014. Epub 2021 Sep 25. Cell Mol Gastroenterol Hepatol. 2022. PMID: 34583087 Free PMC article.
KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity.
Lu S, Kim HS, Cao Y, Bedi K, Zhao L, Narayanan IV, Magnuson B, Gu Y, Yang J, Yi Z, Babaniamansour S, Shameon S, Xu C, Paulsen MT, Qiu P, Jeyarajan S, Ljungman M, Thomas D, Dou Y, Crawford H, di Magliano MP, Ge K, Yang B, Shi J. Lu S, et al. Among authors: bedi k. Int J Cancer. 2023 Aug 1;153(3):552-570. doi: 10.1002/ijc.34528. Epub 2023 May 4. Int J Cancer. 2023. PMID: 37140208 Free PMC article.
Genome-wide transcriptional effects of the anti-cancer agent camptothecin.
Veloso A, Biewen B, Paulsen MT, Berg N, Carmo de Andrade Lima L, Prasad J, Bedi K, Magnuson B, Wilson TE, Ljungman M. Veloso A, et al. Among authors: bedi k. PLoS One. 2013 Oct 23;8(10):e78190. doi: 10.1371/journal.pone.0078190. eCollection 2013. PLoS One. 2013. PMID: 24194914 Free PMC article.
Transcriptomic Analysis of Diffuse Intrinsic Pontine Glioma (DIPG) Identifies a Targetable ALDH-Positive Subset of Highly Tumorigenic Cancer Stem-like Cells.
Surowiec RK, Ferris SF, Apfelbaum A, Espinoza C, Mehta RK, Monchamp K, Sirihorachai VR, Bedi K, Ljungman M, Galban S. Surowiec RK, et al. Among authors: bedi k. Mol Cancer Res. 2021 Feb;19(2):223-239. doi: 10.1158/1541-7786.MCR-20-0464. Epub 2020 Oct 26. Mol Cancer Res. 2021. PMID: 33106374 Free PMC article.
CDK12 regulates co-transcriptional splicing and RNA turnover in human cells.
Magnuson B, Bedi K, Narayanan IV, Bartkowiak B, Blinkiewicz H, Paulsen MT, Greenleaf A, Ljungman M. Magnuson B, et al. Among authors: bedi k. iScience. 2022 Aug 28;25(9):105030. doi: 10.1016/j.isci.2022.105030. eCollection 2022 Sep 16. iScience. 2022. PMID: 36111258 Free PMC article.
A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis.
Galbán S, Apfelbaum AA, Espinoza C, Heist K, Haley H, Bedi K, Ljungman M, Galbán CJ, Luker GD, Dort MV, Ross BD. Galbán S, et al. Among authors: bedi k. Mol Cancer Ther. 2017 Nov;16(11):2340-2350. doi: 10.1158/1535-7163.MCT-17-0207. Epub 2017 Aug 3. Mol Cancer Ther. 2017. PMID: 28775144 Free PMC article.
216 results