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Page 1
BRAF-MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas.
Brastianos PK, Twohy E, Geyer S, Gerstner ER, Kaufmann TJ, Tabrizi S, Kabat B, Thierauf J, Ruff MW, Bota DA, Reardon DA, Cohen AL, De La Fuente MI, Lesser GJ, Campian J, Agarwalla PK, Kumthekar P, Mann B, Vora S, Knopp M, Iafrate AJ, Curry WT Jr, Cahill DP, Shih HA, Brown PD, Santagata S, Barker FG 2nd, Galanis E. Brastianos PK, et al. Among authors: iafrate aj. N Engl J Med. 2023 Jul 13;389(2):118-126. doi: 10.1056/NEJMoa2213329. N Engl J Med. 2023. PMID: 37437144 Free PMC article. Clinical Trial.
The NCI-MATCH trial: lessons for precision oncology.
O'Dwyer PJ, Gray RJ, Flaherty KT, Chen AP, Li S, Wang V, McShane LM, Patton DR, Tricoli JV, Williams PM, Iafrate AJ, Sklar J, Mitchell EP, Takebe N, Sims DJ, Coffey B, Fu T, Routbort M, Rubinstein LV, Little RF, Arteaga CL, Marinucci D, Hamilton SR, Conley BA, Harris LN, Doroshow JH. O'Dwyer PJ, et al. Among authors: iafrate aj. Nat Med. 2023 Jun;29(6):1349-1357. doi: 10.1038/s41591-023-02379-4. Epub 2023 Jun 15. Nat Med. 2023. PMID: 37322121 Free PMC article. Review.
FGFR Alterations in Thyroid Carcinoma: A Novel Class of Primary Drivers with Significant Therapeutic Implications and Secondary Molecular Events Potentially Mediating Resistance in Thyroid Malignancy.
Sabbagh MF, Janovitz T, Dias-Santagata D, Siegmund S, Nardi V, Wirth LJ, Randolph GW, Lennerz JK, Decker B, Nose V, Alzumaili BA, Faquin WC, Barletta JA, Le LP, Iafrate AJ, Sadow PM, Fisch AS. Sabbagh MF, et al. Among authors: iafrate aj. Thyroid. 2024 Sep;34(9):1137-1149. doi: 10.1089/thy.2024.0216. Epub 2024 Aug 7. Thyroid. 2024. PMID: 39003525
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine response in adults with predominantly antibody deficiency.
Zhang AM, Elmoursi A, DiGiacomo DV, Zhou B, Tandon M, Hong JS, Yang NJ, Ong MS, Dighe AS, Berrios C, Poznansky MC, Iafrate AJ, Naranbhai V, Balazs A, Pillai S, Farmer JR, Barmettler S. Zhang AM, et al. Among authors: iafrate aj. J Allergy Clin Immunol Glob. 2024 Feb 20;3(2):100234. doi: 10.1016/j.jacig.2024.100234. eCollection 2024 May. J Allergy Clin Immunol Glob. 2024. PMID: 38544577 Free PMC article.
Ongoing evolution of SARS-CoV-2 drives escape from mRNA vaccine-induced humoral immunity.
Roederer AL, Cao Y, Denis KS, Sheehan ML, Li CJ, Lam EC, Gregory DJ, Poznansky MC, Iafrate AJ, Canaday DH, Gravenstein S, Garcia-Beltran WF, Balazs AB. Roederer AL, et al. Among authors: iafrate aj. medRxiv [Preprint]. 2024 Mar 7:2024.03.05.24303815. doi: 10.1101/2024.03.05.24303815. medRxiv. 2024. PMID: 38496628 Free PMC article. Preprint.
Blood-based screening for HPV-associated cancers.
Das D, Hirayama S, Aye L, Bryan ME, Naegele S, Zhao B, Efthymiou V, Mendel J, Fisch AS, Kröller L, Michels BE, Waterboer T, Richmon JD, Adalsteinsson V, Lawrence MS, Crowson MG, Iafrate AJ, Faden DL. Das D, et al. Among authors: iafrate aj. medRxiv [Preprint]. 2024 Feb 2:2024.01.04.24300841. doi: 10.1101/2024.01.04.24300841. medRxiv. 2024. PMID: 38328243 Free PMC article. Preprint.
T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-19.
Zonozi R, Walters LC, Shulkin A, Naranbhai V, Nithagon P, Sauvage G, Kaeske C, Cosgrove K, Nathan A, Tano-Menka R, Gayton AC, Getz MA, Senjobe F, Worrall D, Iafrate AJ, Fromson C, Montesi SB, Rao DA, Sparks JA, Wallace ZS, Farmer JR, Walker BD, Charles RC, Laliberte K, Niles JL, Gaiha GD. Zonozi R, et al. Among authors: iafrate aj. Sci Transl Med. 2023 Nov 29;15(724):eadh4529. doi: 10.1126/scitranslmed.adh4529. Epub 2023 Nov 29. Sci Transl Med. 2023. PMID: 38019932
318 results