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Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Zhang T, Xu D, Liu J, Wang M, Duan LJ, Liu M, Meng H, Zhuang Y, Wang H, Wang Y, Lv M, Zhang Z, Hu J, Shi L, Guo R, Xie X, Liu H, Erickson E, Wang Y, Yu W, Dang F, Guan D, Jiang C, Dai X, Inuzuka H, Yan P, Wang J, Babuta M, Lian G, Tu Z, Miao J, Szabo G, Fong GH, Karnoub AE, Lee YR, Pan L, Kaelin WG Jr, Yuan J, Wei W. Zhang T, et al. Among authors: jiang c. Nat Cell Biol. 2023 Jul;25(7):950-962. doi: 10.1038/s41556-023-01170-4. Epub 2023 Jul 3. Nat Cell Biol. 2023. PMID: 37400498 Free PMC article.
Ring domains are essential for GATOR2-dependent mTORC1 activation.
Jiang C, Dai X, He S, Zhou H, Fang L, Guo J, Liu S, Zhang T, Pan W, Yu H, Fu T, Li D, Inuzuka H, Wang P, Xiao J, Wei W. Jiang C, et al. Mol Cell. 2023 Jan 5;83(1):74-89.e9. doi: 10.1016/j.molcel.2022.11.021. Epub 2022 Dec 16. Mol Cell. 2023. PMID: 36528027 Free PMC article.
AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness.
Wang X, Jin J, Wan F, Zhao L, Chu H, Chen C, Liao G, Liu J, Yu Y, Teng H, Fang L, Jiang C, Pan W, Xie X, Li J, Lu X, Jiang X, Ge X, Ye D, Wang P. Wang X, et al. Among authors: jiang c, jiang x. Dev Cell. 2019 Feb 11;48(3):345-360.e7. doi: 10.1016/j.devcel.2018.11.033. Epub 2018 Dec 27. Dev Cell. 2019. PMID: 30595535 Free PMC article.
TRAF4-Mediated LAMTOR1 Ubiquitination Promotes mTORC1 Activation and Inhibits the Inflammation-Induced Colorectal Cancer Progression.
Zhao L, Gao N, Peng X, Chen L, Meng T, Jiang C, Jin J, Zhang J, Duan Q, Tian H, Weng L, Wang X, Tan X, Li Y, Qin H, Yuan J, Ge X, Deng L, Wang P. Zhao L, et al. Among authors: jiang c. Adv Sci (Weinh). 2024 Mar;11(12):e2301164. doi: 10.1002/advs.202301164. Epub 2024 Jan 16. Adv Sci (Weinh). 2024. PMID: 38229144 Free PMC article.
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