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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.
Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. Gilbert LA, et al. Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9. Cell. 2014. PMID: 25307932 Free PMC article.
Next-generation libraries for robust RNA interference-based genome-wide screens.
Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. Kampmann M, et al. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3384-91. doi: 10.1073/pnas.1508821112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080438 Free PMC article.
Nucleosomes impede Cas9 access to DNA in vivo and in vitro.
Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tjian R, Weissman JS. Horlbeck MA, et al. Elife. 2016 Mar 17;5:e12677. doi: 10.7554/eLife.12677. Elife. 2016. PMID: 26987018 Free PMC article.
Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma.
Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. Sabnis AJ, et al. Among authors: weissman js. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9015-20. doi: 10.1073/pnas.1603883113. Epub 2016 Jul 22. Proc Natl Acad Sci U S A. 2016. PMID: 27450084 Free PMC article.
998 results