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Page 1
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.
Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, Huganir RL, Müller FU, Wehrens XHT, Liu JO, Luczak ED, Bezzerides VJ, Anderson ME. Reyes Gaido OE, et al. Among authors: bezzerides vj. Sci Transl Med. 2023 Jun 21;15(701):eabq7839. doi: 10.1126/scitranslmed.abq7839. Epub 2023 Jun 21. Sci Transl Med. 2023. PMID: 37343080 Free PMC article.
Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth.
Lin Z, Guo H, Cao Y, Zohrabian S, Zhou P, Ma Q, VanDusen N, Guo Y, Zhang J, Stevens SM, Liang F, Quan Q, van Gorp PR, Li A, Dos Remedios C, He A, Bezzerides VJ, Pu WT. Lin Z, et al. Among authors: bezzerides vj. Dev Cell. 2016 Nov 21;39(4):466-479. doi: 10.1016/j.devcel.2016.09.005. Epub 2016 Oct 6. Dev Cell. 2016. PMID: 27720608 Free PMC article.
MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII.
Konstantinidis K, Bezzerides VJ, Lai L, Isbell HM, Wei AC, Wu Y, Viswanathan MC, Blum ID, Granger JM, Heims-Waldron D, Zhang D, Luczak ED, Murphy KR, Lu F, Gratz DH, Manta B, Wang Q, Wang Q, Kolodkin AL, Gladyshev VN, Hund TJ, Pu WT, Wu MN, Cammarato A, Bianchet MA, Shea MA, Levine RL, Anderson ME. Konstantinidis K, et al. Among authors: bezzerides vj. J Clin Invest. 2020 Sep 1;130(9):4663-4678. doi: 10.1172/JCI133181. J Clin Invest. 2020. PMID: 32749237 Free PMC article.
Efficient and reproducible generation of human iPSC-derived cardiomyocytes and cardiac organoids in stirred suspension systems.
Prondzynski M, Berkson P, Trembley MA, Tharani Y, Shani K, Bortolin RH, Sweat ME, Mayourian J, Yucel D, Cordoves AM, Gabbin B, Hou C, Anyanwu NJ, Nawar F, Cotton J, Milosh J, Walker D, Zhang Y, Lu F, Liu X, Parker KK, Bezzerides VJ, Pu WT. Prondzynski M, et al. Among authors: bezzerides vj. Nat Commun. 2024 Jul 15;15(1):5929. doi: 10.1038/s41467-024-50224-0. Nat Commun. 2024. PMID: 39009604 Free PMC article.
Antisense Oligonucleotide Therapy for Calmodulinopathy.
Bortolin RH, Nawar F, Park C, Trembley MA, Prondzynski M, Sweat ME, Wang P, Chen J, Lu F, Liou C, Berkson P, Keating EM, Yoshinaga D, Pavlaki N, Samenuk T, Cavazzoni CB, Sage PT, Ma Q, Whitehill RD, Abrams DJ, Carreon CK, Putra J, Alexandrescu S, Guo S, Tsai WC, Rubart M, Kubli DA, Mullick AE, Bezzerides VJ, Pu WT. Bortolin RH, et al. Among authors: bezzerides vj. Circulation. 2024 Oct 8;150(15):1199-1210. doi: 10.1161/CIRCULATIONAHA.123.068111. Epub 2024 Aug 19. Circulation. 2024. PMID: 39155863
Activin type II receptor signaling in cardiac aging and heart failure.
Roh JD, Hobson R, Chaudhari V, Quintero P, Yeri A, Benson M, Xiao C, Zlotoff D, Bezzerides V, Houstis N, Platt C, Damilano F, Lindman BR, Elmariah S, Biersmith M, Lee SJ, Seidman CE, Seidman JG, Gerszten RE, Lach-Trifilieff E, Glass DJ, Rosenzweig A. Roh JD, et al. Sci Transl Med. 2019 Mar 6;11(482):eaau8680. doi: 10.1126/scitranslmed.aau8680. Sci Transl Med. 2019. PMID: 30842316 Free PMC article.
53 results