Hu K - Search Results

1

Enhanced BCAT1 activity and BCAA metabolism promotes RhoC activity in cancer progression.

Qian L, Li N, Lu XC, Xu M, Liu Y, Li K, Zhang Y, Hu K, Qi YT, Yao J, Wu YL, Wen W, Huang S, Chen ZJ, Yin M, Lei QY. Qian L, et al. Among authors: hu k. Nat Metab. 2023 Jul;5(7):1159-1173. doi: 10.1038/s42255-023-00818-7. Epub 2023 Jun 19. Nat Metab. 2023. PMID: 37337119

2

Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK.

Wang J, Hu K, Guo J, Cheng F, Lv J, Jiang W, Lu W, Liu J, Pang X, Liu M. Wang J, et al. Among authors: hu k. Nat Commun. 2016 May 19;7:11363. doi: 10.1038/ncomms11363. Nat Commun. 2016. PMID: 27193833 Free PMC article.

3

BCL6 is regulated by the MAPK/ELK1 axis and promotes KRAS-driven lung cancer.

Li K, Liu Y, Ding Y, Zhang Z, Feng J, Hu J, Chen J, Lian Z, Chen Y, Hu K, Chen Z, Cai Z, Liu M, Pang X. Li K, et al. Among authors: hu j, hu k. J Clin Invest. 2022 Nov 15;132(22):e161308. doi: 10.1172/JCI161308. J Clin Invest. 2022. PMID: 36377663 Free PMC article.

4

Targeting metabolic vulnerability in mitochondria conquers MEK inhibitor resistance in KRAS-mutant lung cancer.

Feng J, Lian Z, Xia X, Lu Y, Hu K, Zhang Y, Liu Y, Hu L, Yuan K, Sun Z, Pang X. Feng J, et al. Among authors: hu l, hu k. Acta Pharm Sin B. 2023 Mar;13(3):1145-1163. doi: 10.1016/j.apsb.2022.10.023. Epub 2022 Oct 28. Acta Pharm Sin B. 2023. PMID: 36970205 Free PMC article.

5

FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway.

Li K, Guo Q, Yang J, Chen H, Hu K, Zhao J, Zheng S, Pang X, Zhou S, Dang Y, Li L. Li K, et al. Among authors: hu k. Oncotarget. 2017 Jan 17;8(3):5048-5056. doi: 10.18632/oncotarget.13790. Oncotarget. 2017. PMID: 27926503 Free PMC article.

6

Blocking STAT3 by pyrvinium pamoate causes metabolic lethality in KRAS-mutant lung cancer.

Feng J, Jiang W, Liu Y, Huang W, Hu K, Li K, Chen J, Ma C, Sun Z, Pang X. Feng J, et al. Among authors: hu k. Biochem Pharmacol. 2020 Jul;177:113960. doi: 10.1016/j.bcp.2020.113960. Epub 2020 Apr 13. Biochem Pharmacol. 2020. PMID: 32298693

7

REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.

Chen H, Gao X, Sun Z, Wang Q, Zuo D, Pan L, Li K, Chen J, Chen G, Hu K, Li K, Shah AS, Huang T, Muhammad Zeeshan B, Tong L, Jiao C, Liu J, Chen T, Yao L, Dang Y, Liu T, Li L. Chen H, et al. Among authors: hu k. Exp Dermatol. 2017 Nov;26(11):1118-1124. doi: 10.1111/exd.13394. Epub 2017 Aug 30. Exp Dermatol. 2017. PMID: 28605165

8

Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma.

Hu K, Li K, Lv J, Feng J, Chen J, Wu H, Cheng F, Jiang W, Wang J, Pei H, Chiao PJ, Cai Z, Chen Y, Liu M, Pang X. Hu K, et al. J Clin Invest. 2020 Apr 1;130(4):1752-1766. doi: 10.1172/JCI124049. J Clin Invest. 2020. PMID: 31874110 Free PMC article.

9

Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation.

Wei G, Gao N, Chen J, Fan L, Zeng Z, Gao G, Li L, Fang G, Hu K, Pang X, Fan HY, Clevers H, Liu M, Zhang X, Li D. Wei G, et al. Among authors: hu k. Development. 2020 Sep 2;147(17):dev185678. doi: 10.1242/dev.185678. Development. 2020. PMID: 32747435

10

Autophagy inhibition enabled efficient photothermal therapy at a mild temperature.

Zhou Z, Yan Y, Hu K, Zou Y, Li Y, Ma R, Zhang Q, Cheng Y. Zhou Z, et al. Among authors: hu k. Biomaterials. 2017 Oct;141:116-124. doi: 10.1016/j.biomaterials.2017.06.030. Epub 2017 Jun 27. Biomaterials. 2017. PMID: 28675807

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