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Multicellular communities are perturbed in the aging human brain and Alzheimer's disease.
Cain A, Taga M, McCabe C, Green GS, Hekselman I, White CC, Lee DI, Gaur P, Rozenblatt-Rosen O, Zhang F, Yeger-Lotem E, Bennett DA, Yang HS, Regev A, Menon V, Habib N, De Jager PL. Cain A, et al. Among authors: bennett da. Nat Neurosci. 2023 Jul;26(7):1267-1280. doi: 10.1038/s41593-023-01356-x. Epub 2023 Jun 19. Nat Neurosci. 2023. PMID: 37336975 Free PMC article.
CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Chibnik LB, Shulman JM, Leurgans SE, Schneider JA, Wilson RS, Tran D, Aubin C, Buchman AS, Heward CB, Myers AJ, Hardy JA, Huentelman MJ, Corneveaux JJ, Reiman EM, Evans DA, Bennett DA, De Jager PL. Chibnik LB, et al. Among authors: bennett da. Ann Neurol. 2011 Mar;69(3):560-9. doi: 10.1002/ana.22277. Epub 2011 Mar 9. Ann Neurol. 2011. PMID: 21391232 Free PMC article.
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.
Treusch S, Hamamichi S, Goodman JL, Matlack KE, Chung CY, Baru V, Shulman JM, Parrado A, Bevis BJ, Valastyan JS, Han H, Lindhagen-Persson M, Reiman EM, Evans DA, Bennett DA, Olofsson A, DeJager PL, Tanzi RE, Caldwell KA, Caldwell GA, Lindquist S. Treusch S, et al. Among authors: bennett da. Science. 2011 Dec 2;334(6060):1241-5. doi: 10.1126/science.1213210. Epub 2011 Oct 27. Science. 2011. PMID: 22033521 Free PMC article.
A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
De Jager PL, Shulman JM, Chibnik LB, Keenan BT, Raj T, Wilson RS, Yu L, Leurgans SE, Tran D, Aubin C, Anderson CD, Biffi A, Corneveaux JJ, Huentelman MJ; Alzheimer's Disease Neuroimaging Initiative; Rosand J, Daly MJ, Myers AJ, Reiman EM, Bennett DA, Evans DA. De Jager PL, et al. Among authors: bennett da. Neurobiol Aging. 2012 May;33(5):1017.e1-15. doi: 10.1016/j.neurobiolaging.2011.09.033. Epub 2011 Nov 4. Neurobiol Aging. 2012. PMID: 22054870 Free PMC article.
A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline.
Keenan BT, Shulman JM, Chibnik LB, Raj T, Tran D, Sabuncu MR; Alzheimer's Disease Neuroimaging Initiative; Allen AN, Corneveaux JJ, Hardy JA, Huentelman MJ, Lemere CA, Myers AJ, Nicholson-Weller A, Reiman EM, Evans DA, Bennett DA, De Jager PL. Keenan BT, et al. Among authors: bennett da. Hum Mol Genet. 2012 May 15;21(10):2377-88. doi: 10.1093/hmg/dds054. Epub 2012 Feb 17. Hum Mol Genet. 2012. PMID: 22343410 Free PMC article.
1,731 results