Spann NJ - Search Results

1

SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity.

Fixsen BR, Han CZ, Zhou Y, Spann NJ, Saisan P, Shen Z, Balak C, Sakai M, Cobo I, Holtman IR, Warden AS, Ramirez G, Collier JG, Pasillas MP, Yu M, Hu R, Li B, Belhocine S, Gosselin D, Coufal NG, Ren B, Glass CK. Fixsen BR, et al. Among authors: spann nj. Nat Immunol. 2023 Jul;24(7):1188-1199. doi: 10.1038/s41590-023-01528-8. Epub 2023 Jun 15. Nat Immunol. 2023. PMID: 37322178 Free PMC article.

2

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities.

Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK. Heinz S, et al. Mol Cell. 2010 May 28;38(4):576-89. doi: 10.1016/j.molcel.2010.05.004. Mol Cell. 2010. PMID: 20513432 Free PMC article.

3

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages.

Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM. Fan W, et al. Among authors: spann nj. EMBO J. 2010 Dec 15;29(24):4223-36. doi: 10.1038/emboj.2010.268. Epub 2010 Nov 2. EMBO J. 2010. PMID: 21045807 Free PMC article.

4

Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.

Stender JD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJ, Boutros M, Perrimon N, Rosenfeld MG, Glass CK. Stender JD, et al. Among authors: spann nj. Mol Cell. 2012 Oct 12;48(1):28-38. doi: 10.1016/j.molcel.2012.07.020. Epub 2012 Aug 23. Mol Cell. 2012. PMID: 22921934 Free PMC article.

5

Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses.

Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH Jr, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. Spann NJ, et al. Cell. 2012 Sep 28;151(1):138-52. doi: 10.1016/j.cell.2012.06.054. Cell. 2012. PMID: 23021221 Free PMC article.

6

The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements.

Wang VY, Huang W, Asagiri M, Spann N, Hoffmann A, Glass C, Ghosh G. Wang VY, et al. Cell Rep. 2012 Oct 25;2(4):824-39. doi: 10.1016/j.celrep.2012.08.042. Epub 2012 Oct 11. Cell Rep. 2012. PMID: 23063365 Free PMC article.

7

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

Kaikkonen MU, Spann NJ, Heinz S, Romanoski CE, Allison KA, Stender JD, Chun HB, Tough DF, Prinjha RK, Benner C, Glass CK. Kaikkonen MU, et al. Among authors: spann nj. Mol Cell. 2013 Aug 8;51(3):310-25. doi: 10.1016/j.molcel.2013.07.010. Mol Cell. 2013. PMID: 23932714 Free PMC article.

8

Sterols and oxysterols in immune cell function.

Spann NJ, Glass CK. Spann NJ, et al. Nat Immunol. 2013 Sep;14(9):893-900. doi: 10.1038/ni.2681. Nat Immunol. 2013. PMID: 23959186 Review.

9

NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids.

Li P, Spann NJ, Kaikkonen MU, Lu M, Oh DY, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, Auwerx J, Glass CK, Olefsky JM. Li P, et al. Among authors: spann nj. Cell. 2013 Sep 26;155(1):200-214. doi: 10.1016/j.cell.2013.08.054. Cell. 2013. PMID: 24074869 Free PMC article.

10

Environment drives selection and function of enhancers controlling tissue-specific macrophage identities.

Gosselin D, Link VM, Romanoski CE, Fonseca GJ, Eichenfield DZ, Spann NJ, Stender JD, Chun HB, Garner H, Geissmann F, Glass CK. Gosselin D, et al. Among authors: spann nj. Cell. 2014 Dec 4;159(6):1327-40. doi: 10.1016/j.cell.2014.11.023. Cell. 2014. PMID: 25480297 Free PMC article.

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