Yang H - Search Results

1

Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editor.

Wei Y, Zhang M, Hu J, Zhou Y, Xue M, Yin J, Liu Y, Feng H, Zhou L, Li Z, Wang D, Zhang Z, Zhou Y, Liu H, Yao N, Zuo E, Hu J, Du Y, Li W, Xu C, Yang H. Wei Y, et al. Among authors: yang h. Protein Cell. 2023 Jun 7;14(6):416-432. doi: 10.1093/procel/pwac043. Protein Cell. 2023. PMID: 37285261 Free PMC article.

2

Functional analysis of Trichoderma reesei CKIIα2, a catalytic subunit of casein kinase II.

Wang M, Yang H, Zhang M, Liu K, Wang H, Luo Y, Fang X. Wang M, et al. Among authors: yang h. Appl Microbiol Biotechnol. 2015 Jul;99(14):5929-38. doi: 10.1007/s00253-015-6544-y. Epub 2015 Apr 2. Appl Microbiol Biotechnol. 2015. PMID: 25833183

3

N-Heterocyclic Carbene-Catalyzed Intramolecular Nucleophilic Substitution: Enantioselective Construction of All-Carbon Quaternary Stereocenters.

Zhao M, Chen J, Yang H, Zhou L. Zhao M, et al. Among authors: yang h. Chemistry. 2017 Feb 24;23(12):2783-2787. doi: 10.1002/chem.201700198. Epub 2017 Feb 3. Chemistry. 2017. PMID: 28094460

4

Highly efficient base editing in human tripronuclear zygotes.

Zhou C, Zhang M, Wei Y, Sun Y, Sun Y, Pan H, Yao N, Zhong W, Li Y, Li W, Yang H, Chen ZJ. Zhou C, et al. Among authors: yang h. Protein Cell. 2017 Oct;8(10):772-775. doi: 10.1007/s13238-017-0459-6. Protein Cell. 2017. PMID: 28875305 Free PMC article. No abstract available.

5

CRISPR/Cas9-mediated targeted chromosome elimination.

Zuo E, Huo X, Yao X, Hu X, Sun Y, Yin J, He B, Wang X, Shi L, Ping J, Wei Y, Ying W, Wei W, Liu W, Tang C, Li Y, Hu J, Yang H. Zuo E, et al. Among authors: yang h. Genome Biol. 2017 Nov 24;18(1):224. doi: 10.1186/s13059-017-1354-4. Genome Biol. 2017. PMID: 29178945 Free PMC article.

6

Tild-CRISPR Allows for Efficient and Precise Gene Knockin in Mouse and Human Cells.

Yao X, Zhang M, Wang X, Ying W, Hu X, Dai P, Meng F, Shi L, Sun Y, Yao N, Zhong W, Li Y, Wu K, Li W, Chen ZJ, Yang H. Yao X, et al. Among authors: yang h. Dev Cell. 2018 May 21;45(4):526-536.e5. doi: 10.1016/j.devcel.2018.04.021. Dev Cell. 2018. PMID: 29787711 Free article.

7

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos.

Zuo E, Sun Y, Wei W, Yuan T, Ying W, Sun H, Yuan L, Steinmetz LM, Li Y, Yang H. Zuo E, et al. Among authors: yang h. Science. 2019 Apr 19;364(6437):289-292. doi: 10.1126/science.aav9973. Epub 2019 Feb 28. Science. 2019. PMID: 30819928 Free PMC article.

8

Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors.

Zhang M, Zhou C, Wei Y, Xu C, Pan H, Ying W, Sun Y, Sun Y, Xiao Q, Yao N, Zhong W, Li Y, Wu K, Yuan G, Mitalipov S, Chen ZJ, Yang H. Zhang M, et al. Among authors: yang h. Genome Biol. 2019 May 22;20(1):101. doi: 10.1186/s13059-019-1703-6. Genome Biol. 2019. PMID: 31118069 Free PMC article.

9

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis.

Zhou C, Sun Y, Yan R, Liu Y, Zuo E, Gu C, Han L, Wei Y, Hu X, Zeng R, Li Y, Zhou H, Guo F, Yang H. Zhou C, et al. Among authors: yang h. Nature. 2019 Jul;571(7764):275-278. doi: 10.1038/s41586-019-1314-0. Epub 2019 Jun 10. Nature. 2019. PMID: 31181567

10

Advances in detecting and reducing off-target effects generated by CRISPR-mediated genome editing.

Li J, Hong S, Chen W, Zuo E, Yang H. Li J, et al. Among authors: yang h. J Genet Genomics. 2019 Nov 20;46(11):513-521. doi: 10.1016/j.jgg.2019.11.002. Epub 2019 Nov 22. J Genet Genomics. 2019. PMID: 31911131 Review.

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