Hu J - Search Results

1

Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editor.

Wei Y, Zhang M, Hu J, Zhou Y, Xue M, Yin J, Liu Y, Feng H, Zhou L, Li Z, Wang D, Zhang Z, Zhou Y, Liu H, Yao N, Zuo E, Hu J, Du Y, Li W, Xu C, Yang H. Wei Y, et al. Among authors: hu j. Protein Cell. 2023 Jun 7;14(6):416-432. doi: 10.1093/procel/pwac043. Protein Cell. 2023. PMID: 37285261 Free PMC article.

2

CRISPR/Cas9-mediated targeted chromosome elimination.

Zuo E, Huo X, Yao X, Hu X, Sun Y, Yin J, He B, Wang X, Shi L, Ping J, Wei Y, Ying W, Wei W, Liu W, Tang C, Li Y, Hu J, Yang H. Zuo E, et al. Among authors: hu x, hu j. Genome Biol. 2017 Nov 24;18(1):224. doi: 10.1186/s13059-017-1354-4. Genome Biol. 2017. PMID: 29178945 Free PMC article.

3

Optimizing genome editing strategy by primer-extension-mediated sequencing.

Yin J, Liu M, Liu Y, Wu J, Gan T, Zhang W, Li Y, Zhou Y, Hu J. Yin J, et al. Among authors: hu j. Cell Discov. 2019 Mar 26;5:18. doi: 10.1038/s41421-019-0088-8. eCollection 2019. Cell Discov. 2019. PMID: 30937179 Free PMC article.

4

Improved HTGTS for CRISPR/Cas9 off-target detection.

Yin J, Liu M, Liu Y, Hu J. Yin J, et al. Among authors: hu j. Bio Protoc. 2019 May 5;9(9):e3229. doi: 10.21769/BioProtoc.3229. eCollection 2019 May 5. Bio Protoc. 2019. PMID: 33655015 Free PMC article.

5

In-depth assessment of the PAM compatibility and editing activities of Cas9 variants.

Zhang W, Yin J, Zhang-Ding Z, Xin C, Liu M, Wang Y, Ai C, Hu J. Zhang W, et al. Among authors: hu j. Nucleic Acids Res. 2021 Sep 7;49(15):8785-8795. doi: 10.1093/nar/gkab507. Nucleic Acids Res. 2021. PMID: 34133740 Free PMC article.

6

Global detection of DNA repair outcomes induced by CRISPR-Cas9.

Liu M, Zhang W, Xin C, Yin J, Shang Y, Ai C, Li J, Meng FL, Hu J. Liu M, et al. Among authors: hu j. Nucleic Acids Res. 2021 Sep 7;49(15):8732-8742. doi: 10.1093/nar/gkab686. Nucleic Acids Res. 2021. PMID: 34365511 Free PMC article.

7

Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates.

Ling X, Chang L, Chen H, Gao X, Yin J, Zuo Y, Huang Y, Zhang B, Hu J, Liu T. Ling X, et al. Among authors: hu j. Mol Cell. 2021 Nov 18;81(22):4747-4756.e7. doi: 10.1016/j.molcel.2021.09.021. Epub 2021 Oct 13. Mol Cell. 2021. PMID: 34648747 Free article.

8

Cas9 exo-endonuclease eliminates chromosomal translocations during genome editing.

Yin J, Lu R, Xin C, Wang Y, Ling X, Li D, Zhang W, Liu M, Xie W, Kong L, Si W, Wei P, Xiao B, Lee HY, Liu T, Hu J. Yin J, et al. Among authors: hu j. Nat Commun. 2022 Mar 8;13(1):1204. doi: 10.1038/s41467-022-28900-w. Nat Commun. 2022. PMID: 35260581 Free PMC article.

9

PEM-seq comprehensively quantifies DNA repair outcomes during gene-editing and DSB repair.

Liu Y, Yin J, Gan T, Liu M, Xin C, Zhang W, Hu J. Liu Y, et al. Among authors: hu j. STAR Protoc. 2022 Jan 17;3(1):101088. doi: 10.1016/j.xpro.2021.101088. eCollection 2022 Mar 18. STAR Protoc. 2022. PMID: 35462794 Free PMC article.

10

The origin of unwanted editing byproducts in gene editing.

Yin J, Hu J. Yin J, et al. Among authors: hu j. Acta Biochim Biophys Sin (Shanghai). 2022 May 25;54(6):767-781. doi: 10.3724/abbs.2022056. Acta Biochim Biophys Sin (Shanghai). 2022. PMID: 35643959 Free PMC article.

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