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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression.
Ramirez-Valdez RA, Baharom F, Khalilnezhad A, Fussell SC, Hermans DJ, Schrager AM, Tobin KKS, Lynn GM, Khalilnezhad S, Ginhoux F, Van den Eynde BJ, Leung CSK, Ishizuka AS, Seder RA. Ramirez-Valdez RA, et al. Among authors: van den eynde bj. Cell Rep. 2023 Jun 27;42(6):112599. doi: 10.1016/j.celrep.2023.112599. Epub 2023 Jun 7. Cell Rep. 2023. PMID: 37279110 Free PMC article.
Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma.
Carroll TM, Chadwick JA, Owen RP, White MJ, Kaplinsky J, Peneva I, Frangou A, Xie PF, Chang J, Roth A, Amess B, James SA, Rei M, Fuchs HS, McCann KJ, Omiyale AO, Jacobs BA, Lord SR, Norris-Bulpitt S, Dobbie ST, Griffiths L, Ramirez KA, Ricciardi T, Macri MJ, Ryan A, Venhaus RR, Van den Eynde BJ, Karydis I, Schuster-Böckler B, Middleton MR, Lu X; LUD2015-005 Project Team. Carroll TM, et al. Among authors: van den eynde bj. Cancer Cell. 2023 Jul 10;41(7):1222-1241.e7. doi: 10.1016/j.ccell.2023.06.006. Cancer Cell. 2023. PMID: 37433281 Free article.
Novel H-2Db-restricted CD8 epitope derived from mouse MAGE-type antigen P1A mediates antitumor immunity in C57BL/6 mice.
McAuliffe J, Panetti S, Steffke E, Wicki A, Pereira-Almeida V, Noblecourt L, Hu Y, Guo SYW, Lesenfants J, Ramirez-Valdez RA, Chandrasekar V, Ahmad M, Stroobant V, Vigneron N, Van den Eynde BJ, Leung CSK. McAuliffe J, et al. Among authors: van den eynde bj. J Immunother Cancer. 2024 Oct 8;12(10):e008998. doi: 10.1136/jitc-2024-008998. J Immunother Cancer. 2024. PMID: 39384196 Free PMC article.
Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes.
Solvay M, Holfelder P, Klaessens S, Pilotte L, Stroobant V, Lamy J, Naulaerts S, Spillier Q, Frédérick R, De Plaen E, Sers C, Opitz CA, Van den Eynde BJ, Zhu J. Solvay M, et al. Among authors: van den eynde bj. J Immunother Cancer. 2023 Jun;11(6):e006728. doi: 10.1136/jitc-2023-006728. J Immunother Cancer. 2023. PMID: 37344101 Free PMC article.
Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer.
Naulaerts S, Datsi A, Borras DM, Antoranz Martinez A, Messiaen J, Vanmeerbeek I, Sprooten J, Laureano RS, Govaerts J, Panovska D, Derweduwe M, Sabel MC, Rapp M, Ni W, Mackay S, Van Herck Y, Gelens L, Venken T, More S, Bechter O, Bergers G, Liston A, De Vleeschouwer S, Van Den Eynde BJ, Lambrechts D, Verfaillie M, Bosisio F, Tejpar S, Borst J, Sorg RV, De Smet F, Garg AD. Naulaerts S, et al. Among authors: van den eynde bj. Sci Transl Med. 2023 Apr 12;15(691):eadd1016. doi: 10.1126/scitranslmed.add1016. Epub 2023 Apr 12. Sci Transl Med. 2023. PMID: 37043555
Systemic tryptophan homeostasis.
Klaessens S, Stroobant V, De Plaen E, Van den Eynde BJ. Klaessens S, et al. Among authors: van den eynde bj. Front Mol Biosci. 2022 Sep 14;9:897929. doi: 10.3389/fmolb.2022.897929. eCollection 2022. Front Mol Biosci. 2022. PMID: 36188218 Free PMC article. Review.
126 results