The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets.
El K, Douros JD, Willard FS, Novikoff A, Sargsyan A, Perez-Tilve D, Wainscott DB, Yang B, Chen A, Wothe D, Coupland C, Tschöp MH, Finan B, D'Alessio DA, Sloop KW, Müller TD, Campbell JE.
El K, et al. Among authors: chen a.
Nat Metab. 2023 Jun;5(6):945-954. doi: 10.1038/s42255-023-00811-0. Epub 2023 Jun 5.
Nat Metab. 2023.
PMID: 37277609
Free PMC article.