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Page 1
Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial.
François B, Lambden S, Fivez T, Gibot S, Derive M, Grouin JM, Salcedo-Magguilli M, Lemarié J, De Schryver N, Jalkanen V, Hicheur T, Garaud JJ, Cuvier V, Ferrer R, Bestle M, Pettilä V, Mira JP, Bouisse C, Mercier E, Vermassen J, Huberlant V, Vinatier I, Anguel N, Levy M, Laterre PF; ASTONISH investigators. François B, et al. Among authors: laterre pf. Lancet Respir Med. 2023 Oct;11(10):894-904. doi: 10.1016/S2213-2600(23)00158-3. Epub 2023 May 31. Lancet Respir Med. 2023. PMID: 37269870 Clinical Trial.
Study protocol of a randomised, double-blind, placebo-controlled, two-arm parallel-group, multi-centre phase 3 pivotal trial to investigate the efficacy and safety of recombinant human alkaline phosphatase for treatment of patients with sepsis-associated acute kidney injury.
Pickkers P, Angus DC, Arend J, Bellomo R, van den Berg E, Bernholz J, Bestle M, Broglio K, Carlsen J, Doig CJ, Ferrer R, Joannidis M, Francois B, Doi K, Kellum JA, Laterre PF, Liu K, Mehta RL, Murray PT, Ostermann M, Pettilä V, Richards S, Young P, Zarbock A, Kjølbye AL. Pickkers P, et al. Among authors: laterre pf. BMJ Open. 2023 Apr 3;13(4):e065613. doi: 10.1136/bmjopen-2022-065613. BMJ Open. 2023. PMID: 37012016 Free PMC article.
Evaluation of the efficacy and safety of TREM-1 inhibition with nangibotide in patients with COVID-19 receiving respiratory support: the ESSENTIAL randomised, double-blind trial.
François B, Lambden S, Garaud JJ, Derive M, Grouin JM, Asfar P, Darreau C, Mira JP, Quenot JP, Lemarié J, Mercier E, Lacherade JC, Vinsonneau C, Fivez T, Helms J, Badie J, Levy M, Cuvier V, Salcedo-Magguilli M, Laszlo-Pouvreau AL, Laterre PF, Gibot S; ESSENTIAL investigators. François B, et al. Among authors: laterre pf. EClinicalMedicine. 2023 Jun;60:102013. doi: 10.1016/j.eclinm.2023.102013. Epub 2023 May 31. EClinicalMedicine. 2023. PMID: 37350989 Free PMC article.
Effect of mesenchymal stem cells on the host response in severe community-acquired pneumonia.
Reijnders TDY, Laterre PF, François B, Sánchez García M, van Engelen TSR, Sie D, Scicluna BP, Ostanin DV, Galinsky KJ, Butler JM, Lombardo E, van der Poll T; SEPCELL study group. Reijnders TDY, et al. Among authors: laterre pf. Thorax. 2024 Oct 16;79(11):1086-1090. doi: 10.1136/thorax-2024-222026. Thorax. 2024. PMID: 39322407 Free PMC article. Clinical Trial.
Circulating dipeptidyl peptidase 3 and bio-adrenomedullin levels are associated with impaired outcomes in critically ill COVID-19 patients: a prospective international multicentre study.
van Lier D, Deniau B, Santos K, Hartmann O, Dudoignon E, Depret F, Plaud B, Laterre PF, Mebazaa A, Pickkers P. van Lier D, et al. Among authors: laterre pf. ERJ Open Res. 2023 Jan 9;9(1):00342-2022. doi: 10.1183/23120541.00342-2022. eCollection 2023 Jan. ERJ Open Res. 2023. PMID: 36628268 Free PMC article.
Dexamethasone Modulates the Cytokine Response but Not COVID-19-Induced Coagulopathy in Critically Ill.
Dechamps M, De Poortere J, Octave M, Ginion A, Robaux V, Pirotton L, Bodart J, Gruson D, Van Dievoet MA, Douxfils J, Haguet H, Morimont L, Derive M, Jolly L, Bertrand L, Laterre PF, Horman S, Beauloye C. Dechamps M, et al. Among authors: laterre pf. Int J Mol Sci. 2023 Apr 14;24(8):7278. doi: 10.3390/ijms24087278. Int J Mol Sci. 2023. PMID: 37108440 Free PMC article.
Airway epithelium damage in acute respiratory distress syndrome.
Gerard L, Lecocq M, Detry B, Bouzin C, Hoton D, Pinto Pereira J, Carlier F, Plante-Bordeneuve T, Gohy S, Lacroix V, Laterre PF, Pilette C. Gerard L, et al. Among authors: laterre pf. Crit Care. 2024 Oct 30;28(1):350. doi: 10.1186/s13054-024-05127-3. Crit Care. 2024. PMID: 39478566 Free PMC article.
Immunological sub-phenotypes and response to convalescent plasma in COVID-19 induced ARDS: a secondary analysis of the CONFIDENT trial.
Misset B, Diep AN, Bertrand A, Piagnerelli M, Hoste E, Michaux I, De Waele E, Dumoulin A, Jorens PG, van der Hauwaert E, Vallot F, Swinnen W, De Schryver N, de Mey N, Layios N, Mesland JB, Robinet S, Cavalier E, Donneau AF, Moutschen M, Laterre PF. Misset B, et al. Among authors: laterre pf. Ann Intensive Care. 2024 Oct 21;14(1):160. doi: 10.1186/s13613-024-01392-1. Ann Intensive Care. 2024. PMID: 39432177 Free PMC article.
320 results