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Page 1
Plasmodium 18S Ribosomal RNA Biomarker Clearance After Food and Drug Administration-Approved Antimalarial Treatment in Controlled Human Malaria Infection Trials.
Chavtur C, Staubus WJ, Ho M, Hergott DEB, Seilie AM, Healy S, Duffy P, Jackson L, Talley A, Kappe SHI, Hoffman SL, Richie TL, Kublin JG, Chang M, Murphy SC. Chavtur C, et al. Among authors: richie tl. Open Forum Infect Dis. 2023 Apr 13;10(5):ofad202. doi: 10.1093/ofid/ofad202. eCollection 2023 May. Open Forum Infect Dis. 2023. PMID: 37265668 Free PMC article.
Safety and Immunogenicity of Radiation-Attenuated PfSPZ Vaccine in Equatoguinean Infants, Children, and Adults.
Jongo SA, Urbano Nsue Ndong Nchama V, Church LWP, Olotu A, Manock SR, Schindler T, Mtoro A, Kc N, Devinsky O, Zan E, Hamad A, Nyakarungu E, Mpina M, Deal A, Bijeri JR, Ondo Mangue ME, Ntutumu Pasialo BE, Nguema GN, Rivas MR, Chemba M, Ramadhani KK, James ER, Stabler TC, Abebe Y, Riyahi P, Saverino ES, Sax J, Hosch S, Tumbo A, Gondwe L, Segura JL, Falla CC, Phiri WP, Hergott DEB, García GA, Maas C, Murshedkar T, Billingsley PF, Tanner M, Ayekaba MO, Sim BKL, Daubenberger C, Richie TL, Abdulla S, Hoffman SL. Jongo SA, et al. Among authors: richie tl. Am J Trop Med Hyg. 2023 May 9;109(1):138-146. doi: 10.4269/ajtmh.22-0773. Print 2023 Jul 5. Am J Trop Med Hyg. 2023. PMID: 37160281 Free PMC article. Clinical Trial.
Safety and protective efficacy of PfSPZ Vaccine administered to HIV-negative and -positive Tanzanian adults.
Jongo S, Church LWP, Milando F, Qassim M, Schindler T, Rashid M, Tumbo A, Nyaulingo G, Bakari BM, Athuman Mbaga T, Mohamed L, Kassimu K, Simon BS, Mpina M, Zaidi I, Duffy PE, Swanson PA 2nd, Seder R, Herman JD, Mendu M, Zur Y, Alter G, Kc N, Riyahi P, Abebe Y, Murshedkar T, James ER, Billingsley PF, Sim BKL, Richie TL, Daubenberger C, Abdulla S, Hoffman SL. Jongo S, et al. Among authors: richie tl. J Clin Invest. 2024 Jan 9;134(6):e169060. doi: 10.1172/JCI169060. J Clin Invest. 2024. PMID: 38194272 Free PMC article. Clinical Trial.
Piloting delivery of PfSPZ vaccines for malaria through a cryogenic vaccine cold chain to travel and military medicine clinics.
James ER, Church LWP, Hoffman SL, Richie TL, Robertson BD, Hickey PW, Schwartz DJ, Logan PT, Asare TD, Jones ML, Bay JL, Roschel AK, Pfeiffer JL, Acosta RW, Schiavi E, Acosta AM, Noble M, Henkel T, Young C. James ER, et al. Among authors: richie tl. J Travel Med. 2024 Apr 6;31(3):taae007. doi: 10.1093/jtm/taae007. J Travel Med. 2024. PMID: 38206875
Implementation of a Randomized, Placebo-Controlled Trial of Live Attenuated Malaria Sporozoite Vaccines in an Indonesian Military Study Population.
Indrihutami K, Chand K, Fahmia R, Rachmat A, Rahardjani M, Wulandari F, Subekti D, Noviyanti R, Sutanto I, Soebandrio A, Mallisa NT, Mardika IM, Budiman W, Suriswan I, Ertanto Y, Chen MC, Murshedkar T, Abebe Y, James ER, Billingsley PF, Sim BKL, Hoffman SL, Richie TL, Chen S, Elyazar IRF, Ekawati LL, Baird JK, Nelwan EJ. Indrihutami K, et al. Among authors: richie tl. Am J Trop Med Hyg. 2024 Mar 26;110(5):892-901. doi: 10.4269/ajtmh.23-0597. Print 2024 May 1. Am J Trop Med Hyg. 2024. PMID: 38531102 Free PMC article. Clinical Trial.
A paradigm for Africa-centric vaccine development in Equatorial Guinea.
Billingsley PF, Richie TL, Abdulla S, Ondo'o Ayekaba M, Daubenberger CA, Garcia GA, Hoffman SL. Billingsley PF, et al. Among authors: richie tl. Trends Parasitol. 2024 May;40(5):362-366. doi: 10.1016/j.pt.2024.03.005. Epub 2024 Apr 5. Trends Parasitol. 2024. PMID: 38582683 Review.
Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine.
Senkpeil L, Bhardwaj J, Little MR, Holla P, Upadhye A, Fusco EM, Swanson PA 2nd, Wiegand RE, Macklin MD, Bi K, Flynn BJ, Yamamoto A, Gaskin EL, Sather DN, Oblak AL, Simpson E, Gao H, Haining WN, Yates KB, Liu X, Murshedkar T, Richie TL, Sim BKL, Otieno K, Kariuki S, Xuei X, Liu Y, Polidoro RB, Hoffman SL, Oneko M, Steinhardt LC, Schmidt NW, Seder RA, Tran TM. Senkpeil L, et al. Among authors: richie tl. JCI Insight. 2024 Apr 30;9(11):e167408. doi: 10.1172/jci.insight.167408. JCI Insight. 2024. PMID: 38687615 Free PMC article. Clinical Trial.
Safety and efficacy of PfSPZ Vaccine against malaria in healthy adults and women anticipating pregnancy in Mali: two randomised, double-blind, placebo-controlled, phase 1 and 2 trials.
Diawara H, Healy SA, Mwakingwe-Omari A, Issiaka D, Diallo A, Traore S, Soumbounou IH, Gaoussou S, Zaidi I, Mahamar A, Attaher O, Fried M, Wylie BJ, Mohan R, Doan V, Doritchamou JYA, Dolo A, Morrison RD, Wang J, Hu Z, Rausch KM, Zeguime A, Murshedkar T, Kc N, Sim BKL, Billingsley PF, Richie TL, Hoffman SL, Dicko A, Duffy PE; PfSPZ Vaccine Study Team. Diawara H, et al. Among authors: richie tl. Lancet Infect Dis. 2024 Aug 14:S1473-3099(24)00360-8. doi: 10.1016/S1473-3099(24)00360-8. Online ahead of print. Lancet Infect Dis. 2024. PMID: 39153490
PfSPZ Vaccine induces focused humoral immune response in HIV positive and negative Tanzanian adults.
Tumbo A, Lorenz FR, Yang ASP, Sefried S, Schindler T, Mpina M, Dangy JP, Milando FA, Rashid MA, Nyaulingo G, Ramadhani K, Jongo S, Felgner PL, Abebe Y, Sim BKL, Church LWP, Richie TL, Billingsley PF, Murshedkar T, Hoffman SL, Abdulla S, Kremsner PG, Mordmüller B, Daubenberger C, Fendel R. Tumbo A, et al. Among authors: richie tl. EBioMedicine. 2024 Oct;108:105364. doi: 10.1016/j.ebiom.2024.105364. Epub 2024 Sep 30. EBioMedicine. 2024. PMID: 39353279 Free PMC article.
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria.
Odera DO, Tuju J, Mwai K, Nkumama IN, Fürle K, Chege T, Kimathi R, Diehl S, Musasia FK, Rosenkranz M, Njuguna P, Hamaluba M, Kapulu MC, Frank R; CHMI-SIKA Study Team; Osier FHA, Abdi AI, Chi PC, de Laurent Z, Jao I, Kamuya D, Kamuyu G, Makale J, Murungi L, Musyoki J, Muthui M, Mwacharo J, Kariuki S, Mwanga D, Mwongeli J, Ndungu F, Njue M, Nyangweso G, Kimani D, Ngoi JM, Musembi J, Ngoto O, Otieno E, Ooko M, Shangala J, Wambua J, Mohammed KS, Omuoyo D, Mosobo M, Kibinge N, Kinyanjui S, Bejon P, Lowe B, Marsh K, Marsh V, Abebe Y, Billingsley PF, Sim BKL, Hoffman SL, James ER, Richie TL, Audi A, Olewe F, Oloo J, Ongecha J, Ongas MO, Koskei N, Bull PC, Hodgson SH, Kivisi C, Imwong M, Murphy SC, Ogutu B, Tarning J, Winterberg M, Williams TN. Odera DO, et al. Among authors: richie tl. Sci Transl Med. 2023 Feb 8;15(682):eabn5993. doi: 10.1126/scitranslmed.abn5993. Epub 2023 Feb 8. Sci Transl Med. 2023. PMID: 36753561 Free PMC article.
172 results